Objectives: To estimate the minimum detectable iodine concentration on multiple dual-energy CT (DECT) platforms. Methods and materials: A phantom containing iodine concentrations ranging from 0 to 10 mg ml−1 was scanned with five dual-energy platforms (two rapid kilo volt switching (r-kVs), one dual source (DS), one sequential acquisition and one split-filter). Serial dilutions of 300 mg ml−1 iodinated contrast material were used to generate concentrations below 2 mg ml−1. Iodine density and virtual monoenergetic images were reviewed by three radiologists to determine the minimum visually detectable iodine concentration. Contrast-to-noise ratios (CNRs) were calculated. Results: 1 mg mL−1 (~0.8 mg mL−1 corrected) was the minimum visually detectable concentration among the platforms and could be seen by all readers on the third-generation r-kVs and DS platforms. Conclusions: At low concentrations, CNR for monoenergetic images was highest on the DS platform and lowest in the sequential acquisition and split-filter platforms. Advances in knowledge: The results of this study corroborate previous in vivo estimates of iodine detection limits at DECT and provide a comparison for the performance of different DECT platforms at low iodine concentrations in vitro.
This investigation presents the design and fabrication of a magnetic resonance imaging (MRI) test phantom for determining slice thickness, slice adjacency, slice offset, and slice angulation. This test phantom is a three-dimensional conic section of MRI image producing material; proper orientation allows analysis in each of the major imaging planes. The phantom design (geometrical configuration) incorporates both theoretical and quantitative methodologies. The necessary mathematical analyses are both simple and rapid. In addition, this phantom has been successfully used to assess the image slice parameters for computed tomography (CT) scanners and single photon emission computed tomography (SPECT) imaging systems. Slice profile parameter results, full width at half maximum (FWHM), from this phantom design are compared with conventional methods.
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