Background Explaining the risk and protective factors of substance use (SU) is the most important principle while designing preventive interventions. The aim of this study was to investigate the prevalence rate and determinants of SU in adolescents based on the social development model (SDM). Method In 2018, applying a cross-sectional design, cluster multistage random sampling was employed to recruit 600 adolescents in Bam County, Iran, to participate in the study. A valid and reliable SDM-based instrument was used to collect data.Results The prevalence rate of using at least one substance was 42% (in girls 33.6% and in boys 50.3%). Having close friends with SU was found as the riskiest factor. A score increase in involvement in prosocial activities and interactions, attachment and commitment to prosocial others (family and school), and skills for interaction/involvement among adolescents reduced the probability of ever use of SU by 53%, 37% and 49%, respectively. Also, one score increase in perceived rewards for antisocial interaction/involvement, belief in antisocial values and situational perception among the participants increased the probability of ever use SU by 2.22, 2.24 and 1.22 times. Conclusion The SDM was helpful in determining the predictors of SU among Iranian adolescents. In community-based interventions to prevent SU among adolescents, a great focus should be firstly on identifying the probability of SU in close friends. Moreover, the involvement of adolescents in prosocial activities and interactions, attachment and commitment to prosocial others (family and school), and skills for interaction/involvement should be core categories while designing community-based interventional studies.

Background Explaining the risk and protective factors of substance use (SU) is the most important principle while designing preventive interventions. The aim of this study was to investigate the prevalence rate and determinants of SU in adolescents based on the social development model (SDM).Method In 2018, applying a cross-sectional design, cluster multistage random sampling was employed to recruit 600 adolescents in Bam County, Iran, to participate in the study. A valid and reliable SDM-based instrument was used to collect data.Results The prevalence rate of using at least one substance was 42% (in girls 33.6% and in boys 50.3%).Having close friends with SU was found as the riskiest factor. A score increase in involvement in prosocial activities and interactions, attachment and commitment to prosocial others (family and school), and skills for interaction/involvement among adolescents reduced the probability of ever use of SU by 53%, 37% and 49%, respectively. Also, one score increase in perceived rewards for antisocial interaction/involvement, belief in antisocial values and situational perception among the participants increased the probability of ever use SU by 2.22, 2.24 and 1.22 times. ConclusionThe SDM was helpful in determining the predictors of SU among Iranian adolescents. In community-based interventions to prevent SU among adolescents, a great focus should be rstly on identifying the probability of SU in close friends. Moreover, the involvement of adolescents in prosocial activities and interactions, attachment and commitment to prosocial others (family and school), and skills for interaction/involvement should be core categories while designing community-based interventional studies.