Mucoepidermoid carcinoma (MEC) is the most common malignant salivary gland neoplasm. Central MEC (CMEC) is a rare primary intraosseous bony lesion with an incidence of 2%–4.3% of all MECs reported. In this article, we present a rare case of a CMEC in the anterior region of maxilla at a 43-year-old female patient that was arising from a dentigerous cyst. CMECs are extremely rare tumor. They are usually low-grade lesions with favorable prognosis. Odontogenic cysts are one of the origins of this lesion. Treatment of impacted tooth is necessary in the early stage for prevention of this neoplasm.
Lichen planus is chronic and comparatively collective inflammatory mucocutaneous disease. The histopathological features of oral lichen planus were described as comparable to those of cutaneous lichen planus(CLP). Among those saw-toothed rete ridges are introduced as less important histopathologic features of idiopathic OLP in contrast to CLP. Accordingly, existing study aimed to estimate existence of saw tooth rete ridges in OLP in comparison to CLP.; In this retrospective cross-sectional study, 56; E stained slides with clinical and histopathological diagnoses of OLP were randomly collected from the archive of the oral pathology laboratory. CLP cases were selected randomly from a private pathology laboratory and were evaluated for the presence of saw-toothed rete ridges. Collected data were evaluated using Chi-square; Fishers exact test in SPSS 24 at an error level of 0.05%. Chi-square test did not show a substantial difference between oral; cutaneous groups in terms of the shape of the rete ridges (p = 0.511). Outcomes of existing study showed that saw tooth rete ridge was seen in OLP similar to CLP. Future studies concerning clinical subtype and type of keratosis are recommended.
Calcifying epithelial odontogenic tumor (CEOT) or Pindborg tumor is a rare tumor which accounts for < 1% of all odontogenic tumors. It usually affects patients between the 3rd and 4th decades of life, however a wide age range from 8 to 92 years has been reported. This neoplasm may be associated with erupted or unerupted teeth. There are both intraosseous and extraosseous variants of CEOT and the posterior part of mandible is the most common location. We present an interesting case of CEOT involving the left side of the maxilla associated with unerupted canine and premolar in an 11‑year‑old girl.
Introduction: Anaerobic bacteria in the oral microbial flora are involved in many infections of the oral cavity and surrounding structures. Fusobacterium nucleatum is believed to differ from other bacteria in its interaction with oral mucosal epithelial cells. The aim of this study was to determine the prevalence of Fusobacterium nucleotum in the epithelial cells of the oral mucosa of patients with periodontitis compared with healthy individuals. Materials and Methods: In this case-control study, Realtime-PCR technique used to detect the Fusobacterium nucleatum in gingival samples of 15 patients with chronic periodontitis and 15 individuals with clinically healthy gingival specimens. The results analyzed by Fisher's exact and Independent t-tests with a significance level of less than 0.05. Results: The Fisher's exact test showed that the F.nucleatum in patients with periodontitis was higher than the healthy population. Also Independent t-test showed that average titer of bacteria in patients with Periodontitis was significantly more than people without gingival inflammation (p value < 0.001). Conclusion: There is a statistically significant relationship between periodontitis and the presence of F.nucleatum in epithelial cells of oral mucusa.
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