The most common physical deformity includes upper and lowers limbs deformity that could be acquired or congenital. Such deformity produces difficulty in daily life activities including reaching, walking, lifting, and carrying things. The present study aimed to explore life satisfaction and attitude towards disability between congenital and acquired physical disabilities. A sample of eighty (N=80) participants was included in the study out of which (n=40) were congenital and (n=40) were acquired physical disables. The sample was collected from different rehabilitation and paraplegic centers as well as institutions through the purposive sampling technique. Satisfaction with life scale and attitude toward disabled person scales were included. It was hypothesized that there will be a significant difference in terms of life satisfaction between congenital and acquired physical disables. The second hypothesis was the attitude towards disability will be positive among the congenital group than the acquired one. An independent sample t-test (IBM SPSS statistics version 20) was applied to analyze the difference between congenital and acquired physical disables.  Results of the study indicated that congenital physical disabled were found with highly satisfied from their life (α=.000) and possess a positive attitude towards disability (α=.000) than the acquired physical disables.