Menstrual-related issues have significant public-health ramifications. Women who are having menstruation troubles should get their mental health checked by healthcare specialists. In young women, a menstrual-related condition has serious health implications. Young females who have menstrual issues miss job and school, and their behavioural and mental development suffers as a result. Depression and anxiety have an impact on women’s menstrual periods in adults. Symptoms like as cramps, tiredness, backache, swelling abdomen, and painful breasts have also been described in women with menstrual misery. Menstrual distress has been shown to impair women’s daily activities, as well as their reproductive and psychological health, according to research. Menstrual periods are frequently accompanied by a variety of unpleasant symptoms, such as premenstrual syndrome, which includes symptoms such as mild cramping and exhaustion. The severity of these symptoms, on the other hand, differs from woman to woman, depending on their health, food, way of life, and other factors. Women with menstrual-related issues have also reported smoking, alcohol intake, and an increase in hunger. Furthermore, young women experience emotional disturbances such as melancholy, restlessness, and despair. It is a sign of an atypical menstrual cycle if there is no cycle or if the bleeding is atypical or light. As a result, it is critical to maintain contact with a gynaecologist in order to detect any significant changes in a regular menstrual cycle.

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Less vascular resistance, higher vascular permeability and improved cardiac output include anatomical and physiological changes related to pregnancy. These are needed to accommodate an increase in plasma volume and ensure significant organ infusion. Nevertheless, increases in oestrogen levels may lead to an increase in the risk of coagulation and thrombosis. Increased levels of progesterone increase the risk of thrombosis due to vasodilation, vascular stasis and edoema in these situations. The increased resistance in preeclampsia maternal systemic blood arteries can create high blood pressure that can interfere with blood flow in numerous organs (including liver, kidneys, brain and placenta). The risk of issues such as pulmonary edoema, placental abruption, pneumonia of aspiration, renal failure, hepatic failure and stroke in pregnant women is increased by Preeclampsia and eclampsia. Some peripheral neuropathies (carpal tunnel syndrome, peripheral facial palsy) and central neurological conditions (seizure, migraine, stroke, epilepsy) may become more common during pregnancy because of the exacerbation of the pre-existing neurologic condition or the onset of neurological disturbance caused by pregnancy physiological changes (such as headache or vascular disorders). During the three trimesters of pregnancy, neurological disorders are both peripheral and central. Therefore, an early and correct diagnosis is required to improve pregnancy care, treatment and perinatal outcomes. The aims of this paper are to identify, define and manage the most prevalent peripheral and centrally occurring neurological disorders in the pregnancy.

Background: An examination of drug use is done in a particular setting, searching for drug use that isn't fair. At the population level, the use of psychotropic drugs for mental illness can be an effective way of identifying and tracking the level of treatment for these conditions. They also provide information on ethical drug use, informed by the currently available information on a medication's benefits and risks. Objective: A major objective of the research was to gather data on patterns of drug use in the psychiatry outpatient department of a tertiary care hospital in Srinagar, Jammu & Kashmir, India. Methodology: The drug use research was performed in a tertiary care hospital in Srinagar, Kashmir, India, in a psychiatry outpatient clinic. This research was observational, cross_sectional, and open_ended in nature. All patients who attended the Psychiatry OPD and fulfilled the inclusion criteria over the course of a six_month cycle were included in the study. Results: Over a period of six months, 600 patients from the psychiatry outpatient department of a tertiary care hospital in Srinagar, Jammu & Kashmir, India were assessed. All patients were classified into seven age groups: up to 14 years old (A), 15 to 25 years old (B), 26 to 35 years old (C), 36 to 45 years old (D), 46 to 55 years old (E), 56 to 65 years old (F), and over 65 years old (G). Clonazepam was the most commonly prescribed medication (152 cases), followed by olanzapine (132 cases), lorazepam (105 cases), and escitalopram (92 cases). Conclusion: Measuring drug use in treatment centres not only explains drug use rates and prescribing behaviour, but it also helps in the identification of causes of polypharmacy and the problems associated with it. Making a habit of setting standards and gauging the quality of clinical treatment using performance feedback should become standard clinical protocol.

Combination of aspirin, clopidogrel and enoxaparin remains the standard treatment for acute coronary syndrome (ACS) but is known to increase the incidence of upper gastrointestinal bleed (UGIB). We hereby report an unusual case of gastrointestinal bleed (GIB) as it resulted inspite of proton pump inhibitor (PPI) prophylaxis within the second day of treatment in a post-menopausal woman (PMW) with high first dose of aspirin clopidogrel dual combination in a patient of ACS.