Episcleritis is an inflammatory condition that affects episcleral tissue underlying the sclera and conjunctiva.1,2 It is a recurrent and mild self-remitting surface disease. Its etiology is unknown but may be associated with systemic diseases.3–5 It has been recognized for over a century as sub-conjunctivitis or subconjuctivitis phlegmatous. The condition is unilateral in two thirds of cases and bilateral in one third. Two major clinical types are noticed diffuse and nodular. The case outlined Nodular episcleritis and its clinical diagnosis and management. The condition was mild and didn’t progress to a more severe disorder. An episcleral nodule adjacent to the cornea is very rare.

Forme Fruste keratoconus is a keratoectatic condition of keratoconus that is a rare, unilateral subclinical, abortive, and unusual syndrome. This case outlined a brief discussion of moderate cornea deformation due to mechanical form by prolonged contact lens use dominantly in one eye. It showed topography’s efficacy in discriminating clinical indices to determine corneal mild ecstatic condition, mainly by a practioner. Forme Fruste keratoconus associated with the mild refractive error may benefit from refractive surgery. Meticulous care must be considered before evaluating the preliminary examination of refractive surgery.

Leber congenital amaurosis (LCA), and glaucoma. Many groups are engaged in such treatments from a handful of research laboratories, namely small biotechs and pharmaceutical companies. The reason for this is perhaps the significant benefits the eye can get from gene therapy are why attracting researchers' interest in the field of gene therapy. The eye has now moved to center stage.