Background: A brain tumor is an intracranial solid neoplasm which involves varied types of cells. Management strategies and prognosis of tumor depends on the combination of factors like the type and grade of tumor, its location, size and state of development. So definite typing of brain tumor by histological examination is essential for appropriate treatment. Methods: This cross-sectional study was carried out from May 2011 to June 2012 in Delta Hospital Limited, Dhaka, Bangladesh. A total of 65 brain tissue biopsy samples were collected irrespective of age and sex along with patients' clinical diagnoses, CT scan or MRI report, and operative findings and histological diagnosis were done. The frequency and proportion were calculated using SPSS 12.0 for Windows. Results: Majority (38.5%) of the study subjects belonged to 40-49 years of age group with male predominance (63.1%). Astrocytoma comprised the largest group (27.7%) and majority of the tumors were in spinal region (23.1%). Conclusions: It is concluded from this study that among the different varieties of brain lesions astrocytoma is the most common one and the location of tumor is more common in spinal region with male predominance between the age group of 40-49 years confirmed by biopsy and histopathology along with CT or MRI.
Rosai-Dorfman disease (RDD) is a rare benign proliferative histiocytic disorder characterised by massive lymphadenopathy. While extranodal involvement can occur in generalised RDD, isolated soft tissue RDD (STRDD) is extremely rare. We report a 17-year-old male patient who presented to the maxillofacial outpatient department of the Sultan Qaboos Hospital, Salalah, Oman, in 2015 with a painless cheek mass which had been slowly growing over the previous two months. Routine histopathological examinations and immunohistochemistry confirmed a diagnosis of STRDD. Currently, surgical excision is considered to be the most effective curative treatment for STRDD, as the outcomes of other treatment modalities are still unknown. Despite its rarity, STRDD should be considered in the differential diagnosis of histiocytic soft tissue lesions.
Background: Mislabeled specimens are one of the most common pre-analytic errors in a histopathology laboratory. As histopathology provides the final diagnosis for most of the diseases, labeling errors can lead to serious consequences leading to wrong treatments. Objectives: This study was carried out to find common pre-analytical errors of histopathology laboratory in the context of our country. Methods: Data were collected on six points of container labeling and nine points of requisition papers through simple check list over a period of one week. Results: Among 142 samples, labeling was found in 82.40% container. Among these labels, patients name, age, hospital registration number of the patients were absent in 19.01%, 26.06% and 90.85% samples respectively. Site of origin of the tissue in the container was absent in 71.83% samples. About 4.93% samples came to the laboratory without fixatives. Patients name, age, sex, site of origin of tissue, name of the referring physician and their contact numbers were found absent in 0.70%, 3.52%, 33.10%, 7.75%, 50% and 95.77% of requisition papers respectively. Clinical diagnosis was absent in 54.23% cases. A good proportion of container and requisition papers did not contain proper labeling, which is important not only for identification but also for histopathological diagnosis. Conclusion: We believe that, these errors occur due to lack of standard histopathology requisition form. Association of Surgeons and Pathologists can collaboratively form a standard requisition form for sending histopathology samples to different laboratories, which could easily reduce mislabeling errors in histopathology. Journal of Surgical Sciences (2013) Vol. 17 (2) :80-83
Syringocystadenomapapilliferum is an extremely rare benign adnexal tumor of the scalp and face region. This is a report of the case of a female patient with syringocystadenomapapilliferum originating from the bony cartilaginous junction of the external auditory canal. A provisional diagnosis of an inflammatory polyp was made based on the clinical and radiological findings. Diagnosis was established only after the histopathological examination. This article represents a report of a rare skin disease and a rare site of affection. It emphasizes the role of histopathology in the diagnosis of such a condition with debatable clinical and radiological findings.
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