Our preliminary data showed that after LSG LESP significantly decreased, and the DeMeester score significantly increased. Although LSG results appear appealing in terms of weight loss, patients should be warned that they might need proton pump inhibitors after the operation. Surgeons should probably lower their threshold for indicating RYGB in patients with known preoperative GERD.
Our preliminary data showed that LRYGB is a suitable treatment option for obese patients with BE, demonstrated by 36 % regression rate of this premalignant disease. Although BE persisted in the remaining patients, no progression to dysplasia was observed. A larger number of patients and longer follow-up are needed for more definitive conclusions.
Obesity is a worldwide increasing concern, and its prevalence has risen rapidly over the past several decades. Since nonsurgical treatment for weight loss in morbidly obese patients has poor long-term outcomes, bariatric surgery has gained acceptance and popularity in the last years. The laparoscopic Roux-en-Y gastric bypass has proved to be safe and effective, with successful long-term outcomes in morbidly obese patients. Key elements for the success of the operation are careful patient selection, a comprehensive preoperative evaluation, and a properly executed operation that respects the key technical elements.
The number of obese people in the world has risen significantly over the past three decades. Obesity is associated with severe health comorbidities and metabolic disorders such as diabetes, hypertension, dyslipidemia, and nonalcoholic fatty liver disease. Even with aggressive pharmacotherapy, obese patients will have substantial poor health outcomes. Bariatric surgery has been used more often during the last 10 years as it has been shown to be safe and effective in decreasing weight. The term "metabolic surgery" has recently emerged from the recognition that the effects of surgery on comorbidities extended beyond weight loss. Most patients suffering from metabolic disorders will obtain significant improvements after surgery.
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