Sewage waters are the primary habitats to harbour antibiotic resistance bacteria (ARB) especially
multi-drug resistance (MDR) human enteric pathogens. Microorganisms acquire resistance towards
many commercial antibiotics due to their inappropriate use. In this study, human enteric pathogens
were isolated, identified and characterized and shows the resistance against five different clinically
significant commonly prescribed antibiotics. The bacterial strains were isolated from different sewage
treatment plants located in Delhi city, India. Samples were analyzed for the detection of pathogenic
human enteric bacteria through morphological, biochemical and molecular analysis. Methanolic leaf
extract of Murraya koenigii showed the significant antibacterial activity against multi drug resistant
human enteric pathogens. Thus, Murraya koenigii leaves would be a potential alterantive to antibiotic
regimens for the prevention of gastrointestinal infections.
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