Background: Thyroid gland is the largest gland of the body which secretes thyroid hormones named T3 & T4. Incidence of solitary thyroid nodule is common in Bangladesh. Objectives: To validate the ultrasonography evaluation of solitary thyroid nodule comparing with histopathological diagnosis. Methodology: This cross sectional study enrolled 75 patients of age range between 14 to 72 years during July 2016 to June 2018 and the study was carried out in the department of Radiology & Imaging of Ultrasonography evaluation was finally compared with histopathological diagnosis which was considered as gold standard. Results: Among 75 patients are included in this study the age ranged between 14 to 72 years. Majority of the patients 37 (49.3%) were found between 31 to 40 years. 65 (86.3%) were female & 10 (13.3%) were male. All patients were presents with thyroid swelling. In USG findings Microcalcifications were present 9 (12%) in benign & 5(6.7%) in malignant cases. Presence of Halo were in all benign cases 14 (18.7%). Comet tail sign were in 5 (6.7%) in benign & 3 (4%) in malignant cases. Histological nodular goiter were 57 (76%), Follicular adenoma 8 (10.7%), Thyroditis 5 (6.7%) and Papillary carcinoma 4 (5.3%), Follicular Carcinoma 1 (1.3%). Conclusion: This cross sectional study was carried out with an aim to determine the usefulness of ultrasonogram diagnosis of solitary thyroid nodule compared with histopathology findings. As the validity test results are higher, it can be concluded that the ultrasonogram is a useful diagnostic modality in the evaluation of solitary thyroid nodule. Bangladesh J Otorhinolaryngol; October 2019; 25(2): 76-84

Background: Mammography is used for the detection of breast cancer. Objective: The purpose of the present study was to evaluate the diagnostic performance of Mammography in the diagnosis of benign and malignant breast mass. Methodology: This cross-sectional type of study was carried out in the Radiology & Imaging department of Sir Salimullah Medical College and Mitford Hospital, Dhaka, during July 2013 to June 2015. Patients clinically suspected as having breast mass, referred in the above mentioned hospitals and enrolled for surgical management were included in this study. Mammography were done in all these patients and they were followed up from the admission up to the post-operative tissue diagnosis of breast mass in respective pathology departments for histopathological correlation. Results: A total of 41 patients had mass among them, 3(7.3%) cases were malignant and 38(92.7%) cases were benign patients. Histopathological diagnosis of invasive ductal carcinoma, invasive lobular carcinoma and medullary carcinoma were 8(14. %), 4(7.00%) and 1(1.8%) respectively. Mammography malignant was found 14 cases out of which 10(76.9%) malignant and 4(9.1%) benign evaluated by histopathology. Mammography benign was found 43 cases out of which 3(23.1%) malignant and 40(90.9%) benign evaluated by histopathology. The sensitivity was 76.9%, specificity 90.9%, accuracy 87.7%, positive predictive values 71.4% and negative predictive values 93.0% in mammography. Conclusion: Mammography is highly sensitive, specific, reliable and useful method in the differentiation of malignant and benign breast masses.

Diagnostic usefulness of multidetector computed tomography (MDCT) scan in the evaluation of neck mass was assessed in this study in terms of sensitivity, specificity, positive and negative predictive value and accuracy in respect to characterise the lesion as benign and malignant, based on different parameters by comparing computed tomography and histopathological findings. This cross sectional study was carried out on 57 patients in the Department of Radiology and Imaging, Sir Salimullah Medical College and Mitford Hospital, Dhaka from January 2014 to December 2015, with a 16 slice multidetector CT scanner and the reports were compared to histopathological diagnosis. Out of 57 patients, 37 (64.9%) and 20 (35.1%) were diagnosed as malignant and benign lesions respectively, with a sensitivity of 94.6%, specificity 95%, positive predictive value 97.2%, negative predictive value 90.5% and diagnostic accuracy of 94.7%. As an imaging modality, thus, MDCT proved to be a useful tool for assessing and characterization of neck mass as benign and malignant, especially in this part of the continent, and is essential in planning surgical approach and predicting prognosis.