No abstract

No abstract

A simple, rapid and sensitive method is described for the determination of omethoate, dimethoate, diazinon, chlorpyrifos, parathion-ethyl, chlorfenvinphos, quinalphos and azinphos-ethyl in postmortem whole blood samples. The analytes and internal standard (ethion) were isolated from the matrix by solid-phase extraction, and were analysed by gas chromatography/mass spectrometry in the selected ion monitoring mode. The method has shown to be selective after analysis of postmortem samples of 40 different origins. Calibration curves were established between 0.05 (0.1 for omethoate) and 25 µg/mL, and the values obtained for intra- and interday precision and accuracy were within the criteria usually accepted for bioanalytical method validation. Lower limits of quantitation were 50 ng/mL for all compounds, except for omethoate (100 ng/mL); the limits of identification of the method were 25 ng/mL for all analytes, except for omethoate, for which 50 ng/mL was obtained. Absolute recovery was determined at three concentration levels, and ranged from 31 to 108%. The proposed method is simple and fast, and can be routinely applied in the determination of these compounds in postmortem whole blood samples within the scope of forensic toxicology. In addition, mass spectrometry has demonstrated to be a powerful and indispensable tool for the unequivocal identification of the analytes, since the acceptance criteria were accomplished even at very low levels, thus allowing obtaining forensically valid and sound results.

ResumoA pesquisa de informação na Internet tem assumido um papel preponderante por parte dos turistas quando planeiam as suas viagens. Devido à interação social a vários níveis e em vários contextos, os media sociais surgem como aplicações de grande importância na divulgação de informação turística. Desta forma, pretende-se avaliar a implementação e a utilização dos media sociais pelas Organizações de Gestão de Destinos (OGD) portuguesas. Neste âmbito, um inquérito por questionário foi aplicado às OGD selecionadas de modo a determinar: quais as aplicações mais utilizadas de media sociais, qual o retorno obtido na utilização deste tipo de aplicações e como é feita a gestão de produção e publicação dos conteúdos. As OGD em causa foram também caracterizadas quanto à sua dimensão territorial, ao número de funcionários, ao orçamento anual de operação e à sua pegada social.Palavras-chave: interação; media sociais; organização de gestão de destinos; turismo; web 2.0. AbstractSearching information on the Internet has taken a lead role in planning trips by tourists. Due to social interaction at several levels and in different scopes, the social media applications have emerged as very important applications for spreading tourist information. Accordingly, our aim is to evaluate the implementation and the use of social media applications by the Portuguese Destination Management Organizations (DMO). A questionnaire was applied to the selected DMO in order to know: which social media applications were the most popular, which return they get as a consequence of using this type of applications, and who manages the production and publishes the contents. The DMO were analyzed according to their territorial dimension, human resources, annual budget and social foot-print.