Background Patients experience severe pain in early postoperative rehabilitation after total knee arthroplasty (TKA). This study aimed to compare the effect of femoral nerve block with different concentrations of chloroprocaine on postoperative rehabilitation in patients with TKA. Material/Methods Ninety patients who only received unilateral TKA were randomly and equally divided into C1 (1% chloroprocaine 0.2 ml/kg), C2 (2% chloroprocaine 0.2 ml/kg), or NS (0.9% sodium chloride solution 0.2 ml/kg) groups. The patients received rehabilitation 3 times a day on days 3–6 after surgery, and femoral nerve block was performed with corresponding solution 10 min before each training session. We recorded the maximum knee flexion angles (MKFA) and maximum knee extension angles (MKEA) during active exercise on day 7 after surgery, as well as the incidence of MKFA ≥100°, American knee society (AKS) scores, and postoperative rehabilitation satisfaction. Adverse effects after administration in each group were also recorded. Results Compared with group NS, patients in group C1 and C2 had larger MKFA during active exercise on day 7 after TKA, and had better rehabilitation satisfaction ( P <0.05). MKEA, the incidence of MKFA ≥100°, and AKS scores showed no significant differences in the 3 groups. There were more patients with decline of muscle strength in group C2 ( P <0.05), and no other adverse reactions were recorded. Conclusions Chloroprocaine for femoral nerve block can be safely used in rehabilitation after TKA and to improve the knee flexion angle in the early postoperative period. Because they may have fewer adverse effects, 1% chloroprocaine 0.2 ml/kg may be preferred.

Background Hypoxic hypoperfusion injury in the brain is a cause of potential injury and even death in the growth period of newborns. Therefore, monitoring regional cerebral oxygen saturation (CrSO 2 ) during this period is particularly important. This observational clinical study from a single center aimed to investigate the factors associated with CrSO 2 in full-term newborn infants during birth transition. Material/Methods We enrolled 84 full-term newborn infants delivered by cesarean section. We started the stopwatch with the obstetrician clamping the newborns’ umbilical cords and recorded the values of newborns’ CrSO 2 , pulse oxygen saturation (SpO 2 ) , pulse rate (PR), end-tidal carbon dioxide (EtCO 2 ), and respiratory rate (RR) at 2 min, 5 min, and 10 min. We weighed the newborns before they left the operating room and used statistical methods to compare the correlation between each observation factor. Results Pearson correlation coefficients between CrSO 2 and SpO 2 measured at 2 min, 5 min, and 10 min were 0.491, 0.599, and 0.587, respectively ( P <0.01). Pearson correlation coefficients between CrSO 2 and EtCO 2 measured at 2 min, 5 min, and 10 min were −0.304, −0.443, and −0.243, respectively ( P <0.05). Regardless of a newborn’s weight, PR, or RR, the correlation between any of those factors and the value of CrSO 2 measured at the corresponding time point had no significance ( P >0.05). Conclusions This study showed a correlation between CrSO 2 and SpO 2 and CrSO 2 and EtCO 2 during birth transition of full-term infants delivered by elective cesarean section, but CrSO 2 had no significant correlation with neonatal weight, PR, or RR.

There are three motion stages for an industrial robot manipulator, including the acceleration stage, the constant velocity stage, and the deceleration stage. Aiming at reducing the residual vibration of the manipulator after the movement of the deceleration, a new method is proposed by configuring the movement parameters of the flexible manipulator. Firstly, we conduct experiments to verify a numerical vibration model of the manipulator, and then, we analyze the vibration suppression effect under different conditions based on the numerical model. The results show that in the range of one movement, the residual vibration can be well suppressed when the acceleration and deceleration time are set as a positive integer to the natural period of the manipulator operation; otherwise, the vibration suppression effect is not obvious and proportional to the difference between the acceleration/deceleration time and the manipulator natural period.

Background: Patients who undergo total knee arthroplasty (TKA) experience severe pain after surgery. Especially active pain in early postoperative rehabilitation training of the knee joint is particularly severe, and it should receive people’s attention.Methods: A total of 90 patients who only received unilateral TKA in our hospital were randomly and equally divided into three groups (group C1: 1% chloroprocaine, group C2: 2% chloroprocaine, and group NS: 0.9% sodium chloride solution 0.2 ml/kg; the dosage was fixed at 0.2 ml/kg for all three groups). All patients received femoral nerve catheterization before TKA and started rehabilitation training 48 h after TKA. The visual analogue scale (VAS) scores of active exercises before and after administration were observed and recorded. VAS scores, maximum knee flexion and extension angles, the incidence of knee flexion angle ≥100° in each group, the American knee society(AKS) scores, together with postoperative rehabilitation training satisfaction and adverse effects were recorded at 7 days and 3 months after surgery.Results: Compared with the NS group, VAS scores after administration of patients in the group C1 and C2 were decreased significantly at each time point (P < 0.05), and the maximum knee flexion angles were increased significantly (P < 0.05), as well as the proportion of maximum knee angle ≥100° (P < 0.05). The postoperative rehabilitation training satisfaction of patients in group C1 and C2 were more than that of patients in the NS group (P < 0.05).Conclusion: The administration of 1% chloroprocaine for femoral nerve block before rehabilitation training after TKA could improve the knee flexion angle at the early postoperative stage, increase the proportion of patients who could squat, and cause fewer side effects.