Background Although the existing cases of COVID-19 in China have been reducing since late February 2020, the confirmed cases are surging abroad. Improving public knowledge regarding COVID-19 is critical to control the epidemic. The study aimed to determine the China’s public knowledge of COVID-19 and attitude towards the control measures.Methods A cross-sectional study was conducted in 48 hours, from 29 February 2020, 22:30 to 2 March 2020, 22:30, based on a self-administered web-based questionnaire. The survey was conducted on the WeChat network. Exponential non-discriminative snowball sampling were applied. The questionnaire was voluntarily submitted by WeChat users. The questionnaire covered the basic demographic information, public knowledge about epidemiological and clinical characteristics of COVID-19, psychological state, and attitude towards overall control measures. The primary outcome was the Chinese public knowledge regarding COVID-19 and the attitude towards the control measures and secondary outcome was psychological state of the public during this epidemic.Results The study included 10,905 participants and 10,399 valid questionnaires were included for analysis. Participants with tertiary education, younger age and healthcare workers had better overall knowledge compared with other participants (all P<0.05). About 91.9% of the participants believed in person-to-person transmission and 39.1% believed in animal-to-person transmission. No significant correlation between anxiety and regional number of existing cases was found, while participants in Hubei were more anxious than those in other regions. In general, 74.1% of participants acknowledged the effectiveness of overall control measures and it was negatively correlated with regional number of existing cases (r=-0.492, P=0.007).Conclusions In conclusion, the survey revealed that Chinese public had overall good knowledge regarding COVID-19 except for those indeterminate knowledge. With the dynamic change of global epidemic situation and more researches, further study would be conducted to explore the change of public knowledge and attitude about COVID-19 in the future.

Molecular Imprinting Technology for the preparation of polymers with specific molecular recognition function had become one of the current research hotspots. It had been widely applied in chromatographic separation, antibody...

The present trial was conducted to evaluate the supplementation effects of Macleaya cordata extract (MCE) on growth performance, serum biochemical parameters, and intestinal health of the juvenile American eel (Anguilla rostrata). The 480 juvenile American eels (10.93 ± 0.06 g) were randomly divided into four groups. They were fed on diets supplemented with MCE levels of 0, 25 mg/kg, 50 mg/kg, and 100 mg/kg for ten weeks, respectively. The 50 mg/kg or 100 mg/kg MCE could significantly improve growth performance, and increase the activities of acid phosphatase and alkaline phosphatase, as well as the level of high-density lipoprotein cholesterol. These levels of MCE also decreased the levels of D-lactate acid, triglyceride, and total cholesterol and the activities of aspartate aminotransferase, alanine aminotransferase, and diamine oxidase. The antioxidant ability, muscular thickness, and fold height of the intestine were enhanced by 50 mg/kg or 100 mg/kg MCE. There was no significant difference in the above parameters of groups fed with 50 mg/kg or 100 mg/kg of MCE. The beneficial effects on the intestinal microbiota were demonstrated in the group fed with 50 mg/kg MCE. In conclusion, the 50 mg/kg MCE could be used in the diet to improve the growth performance and health status of the juvenile American eels.

White-light emissive organic−inorganic hybrid metal halides (MHs) have shown promising potential applications in solid-state lighting. As one-dimensional (1D) MHs for white-light emission remain rare and the key role of halogen regulation in 1D hybrid MHs for broadband emission (BE) has not been well established yet, herein, we report a family of 1D hybrid MHs TMGPbX 3 (TMG = 1,1,3,3-tetramethylguanidine, X = Cl − , Br − , or I − ) to systematically explore the influence of halogen on crystal structures and photoluminescence (PL) properties in 1D organic−inorganic hybrid MHs. Under ultraviolet excitation, TMGPbBr 3 and TMGPbI 3 exhibit BE originating from self-trapped excitons (STEs), while TMGPbCl 3 manifests the special blue-white dual emission, which is contributed by STEs in inorganic frameworks and free excitons (FEs) in the organic component. Different emission mechanisms of three 1D MHs are well demonstrated and compared. With a PL quantum yield (PLQY) up to 11.67%, a white light-emitting diode (WLED) based on TMGPbCl 3 was fabricated to show its valuable application in solid-state lighting.

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