Wireless Sensor Network is composed of hundreds or thousands of sensor nodes scattered in a geographical area and one or multiple sinks collecting information or transmitting it through wireless channels. Zigbee and WiMAX are the most advancing communication technologies of Wireless Sensor Network. WiMAX is a standard IEEE 802.16 based technology which supports internet access and VOIP application whereas Zigbee is the only standard IEEE 802.15.4 based technology designed to address the unique needs of low cost, low power WSNs which provide high data rate at complexity and costs. In this paper, a comparative analysis of Zigbee and WiMAX technologies is made in a 100 node network scenario, by incorporating different routing protocols and studying the affect on the QoS parameters such as throughput and PDR(Packet Delivery Ratio).