Oxindole and 1,4-Naphthoquinone both are the versatile heterocyclic scaffolds which not only found in many naturally occurring and pharmaceutically imperative compounds but also have explored as an important precursor in the synthesis of a library of structurally diverse molecular frameworks desirable for biological studies. For a few decades, significant emphasis is given on the synthesis of both of these important privileged scaffolds to accomplish promising new heterocycles with chemical and biomedical relevance. Due to such prevalence and prominence of oxindole and 1,4-naphthoquinone frameworks in medicinal and synthetic chemistry, many researchers have taken efforts to synthesize the oxindolenaphthoquinone molecular hybrid in a single nucleolus. These efforts have led to the development of different approaches and green technologies in recent years, which includes nano catalysts, microwaves and, ultrasound irradiation. In this review, we have focused our attention, specifically, to provide insight into the modern approaches to the synthesis of oxindole-1,4naphthoquinone molecular hybrid and technical advances in this research field till April 2020. The review is mainly made up of four main parts which contain 2-component, 3-component, 4-component, and other multistep miscellaneous approaches utilized to synthesize this oxindole-1,4-naphthoquinone molecular hybrid. These four main parts are also subdivided according to different substituents present on oxindole-1,4naphthoquinone molecular hybrid. This review focused specifically on the collection of literature on the reaction of isatin with 2-hydroxyl-1,4-naphthoquinone(Lawsone) to afford oxindole-1,4-naphthoquinone molecular hybrid.

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In this manuscript, we have demonstrated an efficient and rapid synthetic strategy for preparation of new fluorene–dendron-hybridized blue light-emitting polymers P1–P7 by the reaction of 9,9 long-chain dialkylated fluorenes M2–M8 with dendronized monomer (M1) under microwave-assisted reaction condition. These fluorene–dendron-hybridized polymers P1–P7 were characterized using different spectroscopic techniques. Furthermore, the optophysical properties of these polymers P1–P7 were studied which revealed that these synthesized polymers P1–P7 have potential to emerge as capable materials in the development of diodes, particularly for blue light emission. In the future, similar approaches would be utilized for preparation of light-emitting polymer composite.

We herein report the synthesis of conjugated chromophoric molecule possessing aza stilbenes and oxindole frameworks under catalyst-free condition by the reaction of 4-amino benzene sulfonic acid with isatin, 5-Bromo Isatin and 5-Iodo Isatin. All the newly synthesized compounds were well characterized by using different spectroscopic techniques like FT-IR spectroscopy, NMR spectroscopy. The developed method was found to be efficient, which have tolerated halogen functional groups. Furthermore the developed method afforded pure compounds just by a filtration process by skipping aqueous work-up extraction and column chromatography purification steps. The synthesized new azastilbenes-oxindole conjugated chromophoric frameworks possesses diverse functionality which might be useful for further chemical transformations to prepare a variety of libraries of derivatives desirable for a variety of applications..