Aim: To assess the functional status of patients and to investigate the effectiveness of rehabilitation intervention in coronavirus disease (COVID-19). Materials and Methods: There were 21 patients with clinically-laboratory confirmed coronavirus disease (COVID-19), who participated in the study. Among the examined patients there were 16 (76.2%) women and 5 (23.8%) men. The average age of the patients was 58}5.08 years. The rehabilitation cycle included an initial and final assessment of the patients’ functional status, after which a rehabilitation intervention was carried out, which consisted of breathing exercises and motor activity. Results: The initial assessment of the patients’ functional status in physical exertion during the 1st day showed that the heart rate (HR) was 127.09}0.55 bpm, the respiratory rate (RR) was 28.05}0.39/min, SpO2 was 85.95}0.38 %, systolic arterial pressure (APs) – 145.09}1.48 mmHg, diastolic arterial pressure (APd) – 84.33}0.86 mmHg. Up to the 5th day of the rehabilitation cycle, heart rate decreased at 25.9%, RR – at 16.8%, SpO2 increased at 6.8%, АPs decreased by 14.3%, АPd decreased at – 9.3% (p<0.001). The SpO2 saturation index after respiratory gymnastics increased significantly starting from the first up to the 5th day of rehabilitation from 92.29}0.44% to 97.62}0.29% (р<0.001). Subjective indices under the influence of rehabilitation intervention had reliable dynamics with a tendency to the decrease of manifestations of shortness of breath according to the Modified Borg scale (MBS) at 63.6% (р<0.001), leveling of general fatigue according to the Borg CR10 scale – at 63.4% (р<0.001), an increase in the patient’s mobility index – at 66.4% (р<0.001), an increase in tolerance to the physical exertion for 6-minute walking distance 6MWD – at 93.4% (р<0.001). Conclusions: Thus, rehabilitation assessment and intervention is an extremely important stage in the treatment of patients with the coronavirus disease (COVID-19), which provides an opportunity to improve the functional status of patients by physically influencing the pathogenetic mechanisms of the disease.

The aim: To increase the treatment effectiveness of CHF patients after MI with stenting by using magnesium and potassium salts of gluconic acid, eplerenone, and rivaroxaban in complex therapy. Materials and methods: The research was performed at the premises of Ivano-Frankivsk Regional Clinical Cardiology Centre, Ukraine. 84 patients with CHF after past MI were examined. Results and conclusions: A more pronounced anti-ischemic effect has been linked to the use of combination therapy with rivaroxaban on the background of basic therapy (BT) in patients with CHF after MI, compared with the use of magnesium and potassium salts of gluconic acid or eplerenone. The use of eplerenone in the complex treatment of these patients on the background of BT has been proven to provide a pronounced reverse remodeling of the left myocardium in the postinfarction period.

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