Abstract Background: Leprosy is a chronic infectious disease caused by Mycobacterium leprae (M. leprae). Distribution of leprosy cases in the world in 2015 was highest in the Southeast Asia region, with 156,118 cases. The increase in new cases and the high prevalence of leprosy requires action to break the chain of transmission. Household contact groups are easy to identify by the research group, because the group has good reasons for examining or getting chemoprophylaxis. Objectives: Our objective was to compare Phenolic Glycolipid 1 (PGL-1) antibody levels in household contacts of pausibasilary (PB) and multibacilary (MB) patients. Methods: This study was a analytic observational study with a cross-sectional design. ELISA examination will be conducted at the Leprosy Laboratory of the Institute of Tropical Diseases, Airlangga University, Surabaya. The study was conducted from 3 December 2019 to 31 January 2020, with a total sample of 60 samples. Resuls: PGL-1 antibodies in MB leprosy household contact were greater than PGL-1 antibodies in PB leprosy household contact, and the results showed statistically significant (p = 0.011). Conclusions: There are differences in the levels of PGL-1 antibodies between household contact PB leprosy patients and MB. The household contact PGL-1 antibody levels in MB leprosy are greater than PB leprosy.

Background: Malassezia folliculitis (MF) is a humid-favoured fungal skin disease caused by Malassezia species. Inaccurate treatments, changes in skin flora and disease exacerbation are often occurred due to oversights in the diagnosis. Several diagnostic methods are established for MF.Objective: To identify clinico-laboratory findings of Malassezia folliculitis in Indonesia. Methods:The study was conducted from January 2014 to December 2018 in seven referral teaching hospitals. Medical records of MF-diagnosed patients were obtained and analysed using the binomial test, chi-square test and Cohen's Kappa coefficient in SPSS 26.0.Results: A total of 353 cases of MF were identified in seven referral teaching hospitals in Indonesia, 66.3% of which were males and 33.7% were females, dominated by the 17-25 years old group (44.5%). Itchy sensation (83.9%) was a major subjective complaint. Lesions were majorly found on the trunk-chest, back and shoulder (68.3%), while the clinical manifestation are mostly follicular papule-pustular lesions (62.1%).Patients were 87.4% positive by KOH examination (modified Jacinto Jamora's criteria) and 69.1% positive by Wood's lamp. Generally, sex, age, subjective complaint, lesion location, clinical manifestation and both examinations were statistically significant (p < .001). A significant relationship between all the clinical criteria of the patients in the KOH especially the clinical manifestation was significantly related to Wood's lamp. The Cohen's Kappa assessment suggested that there was an agreement between KOH and Wood's lamp (κ = −0.272, p < .001). Conclusion:The clinical symptoms of Malassezia folliculitis are dominated by pruritus, papulopustular follicular lesions on the trunk and the presence of spore load.

Background Superficial mycoses is a fungal infection of the skin, nails and hair thatcaused by dematophytes, yeast and mold. Superficial mycoses infections are commonlyfound in high temperature and humidity area such as Indonesia. Palembang is one ofregions in Indonesia has a high temperature and humidity, considered the incidenceof this disease is high. A retrospective study of new cases of superficial mycoses, datataken from medical records and register book at Policlinic of Dermatology andVenereology Dr. Moh. Hoesin Palembang during 5 years from January 2014-December2018. There were 1,236 (17.1%) new cases of superficial mycoses. Incidence ofsuperficial mycoses varies with range 6.9%-23%. The most common superficialmycoses is dermatophytes (38,3%). Microsporum canis, Trichophyton rubrum danTricophyton hmentagrophytes are frequent isolates in this study. The most age groupis 36-45 years (17.6%) with male more than female. Superficial mycoses are often foundin students (26.9%), followed by unskilled workers (20.8%). Of the 1,236 new cases,125 patients had comorbidities, such as malignancy 21 (16.8%) patients,cerebrovascular disease and diabetes mellitus each 16 patients (7.4%). Inguinal andabdomen are the most commonly infected regions. 656 (53.1%) patients was giventopical antifungal. The most common topical antifungal was ketoconazole 2% cream(62%) and systemic antifungal was itraconazole (55,3%).Conclusion: Cases ofsuperficial mycoses, especially dermatophytosis and Malassezia were still commonlyfound, especially in Palembang.

Kusta adalah infeksi granulomatosa kronis disebabkan Mycobacterium leprae. Kusta menginfeksi jaringan kulit, mukosa dan saraf perifer sehingga menyebabkan hilang sensasi kulit dengan atau tanpa lesi kulit. Gambaran klinis kusta sangat bervariasi, dan dapat menyerupai berbagai macam lesi yang ada pada penyakit lain. Diagnosis banding lesi kulit sangat luas sehingga sehingga dapat menyebabkan kesalahan diagnosis. Berdasarkan data World Health Organization (WHO) tahun 2018 dilaporkan jumlah kasus baru kusta di dunia sebanyak 210.671 kasus, dengan angka penemuan kasus baru sebesar 2,77 per 100.000 penduduk. Indonesia menduduki peringkat ketiga di dunia sebagai negara dengan kasus baru kusta terbanyak setelah India dan Brazil.  Kurangnya pengetahuan tenaga kesehatan dan kader mempengaruhi jumlah penemuan kasus kusta. Kegiatan pengabdian masyarakat ini dilakukan dengan tujuan memberikan penyuluhan mengenai pemeriksaan kusta secara dini pada tenaga kesehatan dan kader di Prabumulih. Kegiatan dikoordinir oleh bagian Dermatologi, Venereologi dan Estetika Fakultas Kedokteran Universitas Sriwijaya, bekerja sama dengan Rumah Sakit AR Bunda Prabumulih. Pada akhir kegiatan dapat disimpulkan bahwa peserta menjadi lebih memahami tentang kusta dan langkah-langkah pemeriksaan kusta. Kegiatan ini bermanfaat untuk meningkatkan pengetahuan tenaga kesehatan dan kader mengenai kusta dan cara pemeriksaan kusta.

Tinea capitis is a superficial fungal infection of the scalp and hair, which is seenpredominantly in children. In adults, it is usually related to immunocompromisedpatients and have an atypical features. In patients with end stage renal disease (ESRD),uremia is associated with immune suppression due to the impact of uremic milieu. Allspecimens of tinea capitis should be examined for microscopy, wood’s lamp andculture. Reported a case of 50–year-old male, animal husbandry, presented with itchypapules, pustules, patch alopecia and a hair loss for 6 months. Dermatologic featuresshowed papules, pustules, patch alopecia and black dot. The patient treated withketoconazole shampoo for 3 weeks without any improvement. He had an ESRD for 2years. Gram stain examination and culture showed no bacteri. Wood’s lampexamination showed no fluorescent. Potassium hydroxide (KOH) 10% from scalpscrapings and KOH 20% from hair showed a fungal elements, which support diagnosisof black dot tinea capitis. The patient treated with griseofulvin tablet 500 mg twice aday for 8 weeks, cetirizine tablet 10 mg once daily and 3x/week of ketoconazoleshampoo 2% showed improvement in clinical features and microscopic evaluation.