The apparatus described in this paper has been found useful in the determination of diffusion coefficients in liquids, particularly in concentrated solutions, where large concentration gradients are encountered.
The herbicide, dicamba, following administration of C14-labeled compound to rats by esophageal intubation, incorporation in the food, and subcutaneous injection, was in all instances excreted rapidly via the urine. Following subcutaneous injection, a small proportion was excreted via the feces. The urinary excretion was of chemically unchanged dicamba, approximately one fifth of which was conjugated with glucuronic acid. Dynamic balance in the tissues of rats with dietary dicamba appeared to be reached in 2 weeks. The highest levels were in the aqueous rather than in the fatty tissues, and were approximately in proportion to dosage at the levels of 1000 p.p.m. or less. Early dynamic balance and rapid clearance from the tissues of dicamba given by intubation showed an absence of storage in the ordinary use of the term.
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