Background: Nurses are susceptible to several mental problems, such as fear, stress, and depression due to the COVID-19 pandemic, which affects their emotional well-being. However, resilience plays an important role in mitigating the effects of COVID-19. Objective: This study was to examine the mediating role of resilience in the relation between fear, stress, and depression of nurses during COVID-19 health emergencies. Methods: A cross-sectional—predictive study was carried out. The variables analyzed were fear, resilience, stress, and depression. A total of 286 nurses from 2 hospitals in the cities of Juliaca and Puno, Peru. Data analyses were performed using structural equation modeling (SEM). Results: Analyses showed that the variables were significantly related ( P < .01). In addition, a confirmatory analysis of the hypothesized model using structural equation modeling shows that fear and stress are predictors of depression, and that resilience plays a role in mediating the effect of fear on stress ( X2 = 534.69, gl = 372, P = .000; TLI = .902, CFI = .910, RMSEA = .039 [95% CI = 0.032-0.046], and SRMR = .065). Conclusion: Nurses tend to develop fear, stress, and depression. Resilience reduces the impact of these psychological variables. Hospital management should provide psychological support and training for nurses in coping strategies.

Objetivo: determinar la relación entre miedo, estrés y resiliencia en los estudiantes de enfermería sobre su retorno a las prácticas hospitalarias, post emergencia sanitaria en una universidad privada, Juliaca, 2022. Metodología: de enfoque cuantitativo, de tipo correlacional múltiple de corte transversal; así como tiene un diseño no experimental. Se contó con la participación total de 300 estudiantes de enfermería desde tercero hasta séptimo ciclo. Respecto al análisis, el análisis descriptivo se realizó con medidas de tendencia central, mientras que el inferencial con correlación de Rho de Spearman. Resultados: los análisis de correlación determinaron que existe relación entre las variables (p<0.05), así como también se encontró niveles bajos de miedo (60.3%), medios de estrés (71%) y medios   de resiliencia (54.3%). Conclusiones: la resiliencia supone ser un factor importante y se relacione negativamente con el estrés y miedo, por lo que niveles altos de resiliencia permitiría tener niveles bajos de miedo y estrés.