Background: The efficacy of Djulis for skin care is currently based on cellular or animal models, and the clinical aspect is not in place. Aim: This clinical study is to investigate the synergistic effect of fish collagen and Djulis (Chenopodium formosanum Koidz.) for improvement of skin parameters. We used the combination of hydrolyzed collagen and Djulis to develop a new functional formula for skin improvement. Patients/Methods: Fifty volunteers were randomly allocated (in a 1:1 ratio) to the placebo or collagen drink group. Volunteers were required to consume a 50 mL of a collagen drink or placebo drink daily for 8 weeks. For measurements, the indexes of skin conditions were measured at the baseline and 4 and 8 weeks. Results: The improvements of skin hydration, brightness, crow's feet, texture, wrinkles, pores, spots, and collagen content after 8 weeks in collagen group were 17.8%, 5.4%, 14.9%, 9.9%, 29.3%, 10.4%, 9.9%, and 22.3%, respectively. Noticeably, over 68% of subjects got improved for their skin parameters after 8-week intake of collagen drink. The improvement levels indicated competitive skin improvement effects in comparison with previous studies. Conclusion: This clinical study demonstrates the synergistic effect of fish collagen and Djulis (the main components) for the substantial improvements in hydration, brightness, crow's feet, texture, wrinkles, pores, surface spots, and collagen content in skin. The collagen drink comprehensively improved skin parameters for most subjects after 4-week intake and manifested competitive efficiency in comparison with other similar studies. We convince that the collagen drink may delay skin aging process and improve skin aging parameters.

Background: Diabetes mellitus (DM) is one of degenerative disease and the prevalence is increasing each year. WHO predicted that in 2025 the number of diabetes mellitus outpatients in the world can reach up to 300 milions people. Early detection is needed to prevent higher prevalence in type 2 DM. Moreover, nowadays people are tend to have sedentary lifestyle and bad food pattern. The Objective of this research aims to determine risk factors which related the evidence of type 2 DM.Methods:It was an observational study with cross sectional design. Subjects were 179 people of the study were staffs of Gadjah Mada University who did general check-up at Gadjah Mada Medical Center (GMC) health cencer on March and April 2014. Research variable included diabetic family history, ethnic, physical activity, habit of smoking history, obese, eating pattern, fried foods consumption and diabetes. Data of eating pattern and fried foods consumption are obtained by semi quantitative food frequency questionnaire (SQFFQ). Data about diabetic family history, ethnic, habit of smoking are obtained by interview. Data about physical activity is obtained by IPAQ questionnaire and data about obese an fasting blood glucose value are obtained by secondary data from GMC health center.  Data were analyzed using chi square.Results: There was significant association between diabetic family history, fried food’s consumption frequency and the incidence of type 2 diabetes mellitus (p<0.05). There was no significant association between ethnic, physical activity, habit of smoking, obese, eating pattern, fried food consumption (fried foods mass, fried foods energy and fried foods fat) (p>0.05).Conclusions:Risk factors related with type 2 DM evidence are diabetic family history and fried food’s consumption frequency.

<p>Walaupun sampai saat ini konstipasi fungsional masih beragam definisinya, gejalanya sering dikeluhkan karena dirasakan mengganggu kualitas hidup khususnya, pada kelompok dewasa muda, dan bila tidak ditangani dengan baik akan berdampak negatif bagi kesehatan. Asupan serat yang memadai merupakan salah satu alternatif yang efektif untuk mengatasi masalah tersebut, namun asupan sayur dan buah masyarakat di Indonesia masih jauh dari angka kecukupan yang dianjurkan; jumlah asupan serat harian pekerja dewasa muda di Jakarta bervariasi antara 3,3-27,4 g. Tambahan serat pangan dalam diet sehari-hari diharapkan dapat meningkatkan asupan serat sehingga dapat bermanfaat untuk mengatasi keluhan konstipasi.</p><p>Although until now functional constipation still has various definitions, the symptoms are often interfering with quality of life, especially in young adults. If not managed properly, it may have a serious negative impact on health. Adequate fiber intake is an effective alternative to overcome this problem, but vegetables and fruits intake in Indonesia is still far from adequate. A recent pilot study found that the daily fiber intake among young adult workers in Jakarta is varied between 3.3–27.4 g. Additional dietary fiber in daily diet is expected to increase fiber intake so that it can be useful for dealing with complaints of constipation.</p><p> </p>