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Mukta or Pearl, a valuable gem is included in Ratna varga in most of the Ayurvedic texts. As far as the Ayurvedic Pharmaceutical Science is concerned, selection of raw material is the nucleus of the present study which is important step in standardization. Pearl is available in natural and cultured form. However the scarcity and price has limited the use of natural Pearl in medicine. Thus cultured Pearl was used for the study after thorough analysis using ancient as well as modern techniques like Microscopic study. Pearl was subjected to simple and special purification by Swedan in freshly prepared juice of lemon (Citrus acida Linn) and leaves of Jayanti (Sesbania sesban (Jacq.) W. Wight) respectively. Rose water was prepared as a modified infusion method so as to preserve its essential volatile oils. Mukta Pishti (MP) was prepared by triturating purified Pearl with Rose water per day 6 hours for 21 Days. To assure the quality of MP, Rasa-shastra quality control tests like Nishchandratva, Rekhapurnatva and Varitaratva were used. After MP was found to be in compliance with these tests, it was further analyzed using X-ray diffraction (XRD) analysis. Analysis of raw Pearl and MP revealed that both of them contain CaCO3 in Aragonite form. Determination of particle size was done by Dynamic light scattering (DLS) and Nanoparticle tracking analysis (NTA) for raw Pearl and MP respectively. The particle size was reduced greatly from114.019 µm to 62 nm. It may be concluded that raw Pearl and MP have no change in the form which can be attributed to the fact that Pishti preserves properties of Ratna. Also thorough trituration can reduce particle size up to nanometers. Thus it can validate the sukshmata of Pishti and can be correlated with concept of nanomedicine, essential for its quick and cellular activity.

Introduction: One of the most common consequences of blunt and penetrating ocular trauma is traumatic cataracts. It remains a significant cause of visual impairment. Aim: This study aimed to investigate the analysis of prognostic indicators in the final visual outcome of adult traumatic cataracts. Methodology: The study was conducted on a total of 60 patients including 46 males and 14 females above the age of 18 years were diagnosed with traumatic cataracts. Data regarding demographics, causative agent, type of trauma, and clinical course was recorded, and along with it, the OTS (ocular trauma score) was calculated. The outcome was measured with subsequent follow-up in the form of BCVA at 40 days of surgery. Appropriate statistical tests were applied. Results: Penetrating injuries were sustained in 38 patients (63%) while 22 patients (37%) sustained blunt injuries to the eye. The most common affected age group was 30 – 60 years (60%) with male predilection (male to female ratio is 3.28:1). Commonest cause of trauma was road traffic accidents in 12 eyes (20%) followed by a thorn in 4 eyes (6.66%) and stone in 6 eyes (6.66%). In present study lens implantation, visual acuity at presentation, the morphology of cataract, and OTS were found to significantly affect visual outcome while trauma-surgery duration did not affect visual outcome. Conclusion: Traumatic cataracts mainly affected young males in our study. Better visual acuity at presentation, lens implantation after cataract extraction, and higher OTS correspond to higher visual acuity as recorded. Worse outcomes are seen with subluxated morphology. Trauma to surgery time interval is not a significant factor in the adult population.