OBJECTIVE
To evaluate the dosing accuracy of 2 female enteral syringe types for use in neonates.
METHODS
This was an in vitro study evaluating dosing accuracy of ENFit with low dose tip (LDT) and Nutrisafe2 (NS2) syringes. Acceptable dosing variance (DV) was +/− 10%. Outcomes included tests exceeding 10% DV and DV by syringe size, dispensing source, and intended dosing volume.
RESULTS
A total of 300 tests were performed (LDT = 150, NS2 = 150) with 3 syringe sizes (0.5, 1, 3 or 2.5 mL). Compared with NS2, LDT had significantly more tests with unacceptable DV (48% vs 4.7%, p < 0.0001) and higher absolute DV (11.9% vs 3.5%, p < 0.001). Dosing variance was inversely proportional to syringe size, where the smallest syringes were least accurate (0.5 mL LDT 16.1% vs 4.6%, p < 0.001). The largest syringes had acceptable DV (3 mL LDT 8.8% vs 2.5 mL NS2 3.3%, p < 0.001). Bulk bottle with adapters demonstrated a higher DV with LDT compared with NS2 (13.3% vs 3.9%, p < 0.001). Medication cups without adapters were associated with acceptable DV for both LDT and NS2 (9.7% vs 2.9%, p < 0.001).
CONCLUSIONS
The Nutrisafe2 syringe has greater dosing accuracy as compared with ENFit LDT syringe. Smaller syringes are associated with greater dosing inaccuracy, but this effect was within acceptable DV for the NS2 syringe. Bulk bottle adapters did not improve the accuracy of the LDT. More clinical evaluations are needed to determine if the ENFit can be safely used in the neonatal population.
In nuclear forensics or accident dosimetry, building materials such as bricks can be used to retrospectively determine radiation fields using thermoluminescence and/or optically stimulated luminescence. A major problem with brick material is that significant chemical processing is generally necessary to isolate the quartz from the brick. In this study, a simplified treatment process has been tested in an effort to lessen the processing burden for retrospective dosimetry studies. It was found that by using thermoluminescence responses, the dose deposition profile of a brick sample could be reconstructed without any chemical treatment. This method was tested by estimating the gamma-ray energies of an Am source from the dose deposition in a brick. The results demonstrated the ability to retrospectively measure the source energy with an overall energy resolution of approximately 6 keV. This technique has the potential to greatly expedite dose reconstructions in the wake of nuclear accidents or for any related application where doses of interest are large compared to overall process system noise.
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