No abstract

We often encounter elderly patients with femur bowing. According to literature, femoral bowing is correlated with patient characteristics such as aging, race, atypical femoral fracture (AFF), and osteoporosis. However, the clear relationships between these factors and femoral bowing are still unknown. In addition, most previous reports have been based only on X-rays and may not provide accurate information due to femur rotation and inter-operator reliability when compared to the information obtained using computed tomography (CT) scans. The purpose of this study was to examine the factors associated with anterior and lateral bowing in detail, by using three-dimensional preoperative measurement software Zed Hip®︎ (LEXI Co. Ltd., Tokyo, Japan). A total of 364 patients with trochanteric hip or femoral neck fractures, or osteoarthritis, treated in our hospital were included in this study. Of these, 61 patients older than 50 years, who had complete CT volume data for the entire length of the femur on the healthy side and bone mineral density (BMD) measured by trunk dual-energy X-ray absorptiometry (DXA), were investigated. There were 13 males and 48 females, aged 53-97 years (mean 78.7±10.8 years). We defined the starting and ending points of the femoral diaphysis to measure anterior bowing (AB) and lateral bowing (LB) of the femoral diaphysis. The correlation between AB or LB with each patient's characteristics (age, height, weight, lumbar BMD, and femoral BMD) was examined retrospectively. AB did not correlate with any of the patient parameters. LB weakly positively correlated with age and was negatively correlated with height and femoral (greater trochanter) bone density. Weight was in no correlation with either AB or LB. A novel three-dimensional approach was used for measurements that may be more accurate than plain two-dimensional radiographs.

The present report describes an incomplete atypical femoral fracture (AFF) patient who underwent simultaneous autogenous bone transplantation to the resected fracture region during intramedullary nail fixation. A 73-year-old female with a history of multiple myeloma had been undergoing treatment with intravenous drip injections of Zoledronic Acid. She was introduced to our department due to the left lateral thigh pain, with no trauma incidence. An anteroposterior radiograph showed a transverse thin fracture line with localized periosteal and endosteal thickening, which is compatible with subtrochanteric incomplete AFF. A biochemical investigation revealed the existence of severely suppressed bone turnover. She underwent intramedullary nail fixation for fear of a complete fracture. After the fixation, the cortical bone at the fracture region was excised as a wedge-shaped block, and bone marrow extracted from the hollow reamer was simultaneously transplanted to the resected fracture region. Histological examination showed few bone formation features at the fracture line in the excised lateral cortical bone. At 7 months after surgery, radiographs demonstrated complete bone repair, and no clinical problems were observed two years postoperatively. To the best of our knowledge, this is the first report in which autogenous bone marrow transplantation, noninvasive to the iliac crest, was performed in an incomplete AFF patient. We believe that this low invasive procedure can be a useful technique for AFF treatment.