Bombyx mori silk fibers are an important biomaterial and are used in surgical sutures due to their remarkable biocompatibility. The major drawback to the application of biomaterials is the risk of bacterial invasion, leading to clinical complications. We have developed an easy and cost-effective method for fabrication of antibacterial silk fibers loaded with silver nanoparticles (AgNPs) by an in situ and ex situ process using an aqueous extract of Rhizophora apiculata leaf. Scanning electron microscopy revealed that well dispersed nanoparticles impregnated the silk fibers both in situ and ex situ. The crystalline nature of the AgNPs in the silk fibers was demonstrated by X-ray diffraction. The thermal and mechanical properties of the silk fibers were enhanced after they were impregnated with AgNPs. The silver-coated silk fibers fabricated by the in situ and ex situ method exhibited more than 90% inhibition against Pseudomonas aeruginosa and Staphylococcus aureus. Silk fibers doped with AgNPs were found to be biocompatible with 3T3 fibroblasts. The results obtained represent an important advance towards the clinical application of biocompatible AgNP-loaded silk fibers for prevention of surgical wound infections.

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Herein we report, the poly (NTA-2,4-Dichlorophenylacrylate) copolymers were synthesized using N-tert-amylacrylamide and 2,4-Dichlorophenyl acrylate monomers by Free-radical polymerization at 60°C. The synthesized copolymers were subjected to corrosion inhibition studies on Mild steel using 0.5M H2SO4 solution. These copolymers are showed the corrosion inhibition efficiency of 86.0%

A series of copolymers of N-cyclohexylacrylamide (NCA) and 7-methacryloyloxy-4-methyl coumarin (MACU) were prepared by free radical polymerization using AIBN as initiator in DMF. The copolymer compositions were determined by 1HNMR analysis. The reactivity ratios were determined by linear methods like Finemann-Ross and Kelen-Tudos methods. The value of r1 is less than r 2. So MACU is found to have higher reactivity than NCA. Mean sequence lengths of copolymers were calculated from r1 and r2 values. The product of r1. r2 = 1.1, which is greater than 1 indicates that the copolymers are at random distribution of monomeric unit in the copolymer chain. Thermal studies indicates that the Tg values are higher than the homopolymers of NCA. Antimicrobial studies showed that the copolymers are active against both Bacteria and fungi. However, these copolymers showed excellent antibacterial activity