Gynaecological disorder is one of the most severe conditions under reproductive health. So we investigate and collect information from traditional practitioners on the use of medicinal plants for treatment of Gynaecological disorder in Vedaranyam taluk, Nagappattinam district of South India. The field study was carried out for a period of January 2014–January 2015 in Vedaranyam taluk, Nagappattinam district of South India. This is the first traditional medicine study in which statistical calculations about plants are done by RFC, CI, UV and ICF in the study area. The ethnomedicinal information was collected through interviews, informal meetings, open and group discussions and overt observations with semi-structured questionnaires among traditional practitioners. A total of 66 species of plants distributed in 62 genera belonging to 44 families were identified as commonly used ethno medicinal plants by traditional practitioners in Vedaranyam taluk for the treatment of 36 ailments based on the reproductive systems treated. Leaves were the most frequently used plant parts and most of the medicines were prepared in the form of paste and administrated orally. We know the most important species according to their use value such as Moringa oleifera, Smailax zeylanica and Achyranthes aspera were recorded. The present study, we have highlighted some claims which are high use in the study area. Further pharmacological studies of these plants may provide some important drugs for the treatment of common gynaecological disorders.

No abstract

Stabilization of a single rotary inverted pendulum (SRIP) system is a benchmark nonlinear control problem. Inherent instability of SRIP in upright position and the presence of modelling uncertainty pose a challenge for control engineers. Sliding-mode control (SMC) is the most widely accepted robust control technique. Various versions of SMCs to stabilize SRIP have been reported in literature. Advantages of SMC come at the cost of chattering of input, which inhibits its usage in many practical applications. Several works have been done to reduce the chattering in SMC. Application of fuzzy logic in SMC to reduce chattering has been analysed extensively in the literature. Even though implementation of fuzzy SMC (FSMC) in theory/simulations completely eliminates chattering, practical implementation of FSMC does not reduce chattering to zero. In this paper, a filtered FSMC is proposed, which filters the high frequency component in the system input. Experimental results of SMC, FSMC and a fuzzy sliding-mode controller with filter (FSMCF) are given in this paper. Results indicate that filtering the output of FSMCF reduces the chattering effect in the system without affecting the closed loop dynamics.

No abstract

Azadirachtin (AZA) is the most abundant bioactive secondary metabolite (BASM) in neem seed oil extract (NSOE) of Azadirachta indica A. Juss. AZA is localised in different parts of the plant (seeds, fruits, flowers, leaves, stem, bark and root) however, with varying degree of concentration. It has been documented that maximum concentration of AZA is present to the tune of 48000 μg g-1 in the seeds. It has been established that the environmental conditions determines the overall content and composition of BASM in different parts of the plant. Neem plant parts are most commonly used as therapeutic agents in remote villages in India for its ethnomedicinal therapeutic potentials; however, its physicochemical, druggable and pharmacological properties inadequately described. In the present study an attempt has been made to evaluate the physicochemical, druggable and pharmacological properties of Azadirachtin in NSOE of A. indica from ADMET perspectives. Keywords: NEEM; Azadirachta indica; Azadirachtin; Pharmacoinformatics; ADMET; Drug-Likeness; Toxicology