Following the enucleation, retained conjunctival epithelium became embedded in the connective tissue of the orbit and caused a cyst to develop. The cyst wall consisted of a myofibroblastic collagen-rich matrix and acted as a nidus of chronic irritation and tumor growth. This orbital osteosarcoma resembles feline vaccine-associated sarcomas (VAS), feline post-traumatic ocular sarcomas, and microchip-associated sarcomas in terms of it histopathology and its hypothesized pathogenesis related to exposure to antigenic material such as implanted epithelium, lens protein, vaccine components, and microchips as foreign bodies.
Bovine lactoferrin has a notable inhibitory effect on the in vitro replication of FHV-1 prior to and during, but not following viral adsorption. These findings strongly suggest that lactoferrin inhibits FHV-1 adsorption to the cell surface and/or penetration of the virus into the cell. Clinical effects of topical lactoferrin in acute or recrudescent herpetic episodes in cats warrant investigation.
As mice and rats become more popular as pets, it is expected that they will be seen more often in general veterinary practice. It is hoped that this increase in doctor visits will be associated with an increased number of clinical reports that describe ophthalmic disorders observed in these species. Until then, clinicians must rely on extrapolation and cautious application of data that are generated in laboratory strains.
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