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Morphometric analysis of nucleolar organizer (NO), Balbiani rings (BR) - BR_B, BR_1G, BR_2G, chromosome I arm puff B, chromosomes compactness activity change under the influence of cholinotropic preparations was carried out. Most sensitive criterion - chromosomes compactness is, most stable under the influence of stress - NO is. Atropine and pilocarpine antagonistic effect on the polytene chromosomes (PC) sites activity pilocarpine manifested itself in functional activity and restoration period duration change: on cholinoblocker effect activity decreased, while on cholinomimetic effect activity increased.

The influence of a new enterosorbent-enterosgel on the immune and autoimmune process in the dynamics of ischemic heart disease and the possibilities of endogenic intoxication decrease using the given drug are estimated. The use of enterosgel made it possible to get the high therapeutic hypolipidemic and autoimmunocorrecting effect in patients with ischemic heart disease, expressed in the improvement of the state - the decrease of the frequency of stenocardia making it case of peace and effort making it possible to decrease daily nitroglycerine dose.