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The aim: To analyze the results of inflammatory and immunological parameters of the oral cavity after cystectomy with different methods of connecting the edges of the operated area. Materials and methods: The research was conducted in 87 patients who sought surgical treatment of odontogenic cysts of the jaws. Patients were divided into groups depending on the method of wound closure after surgery. We analyzed the results of laboratory tests (leukocytes, ESR, IL-1β, IL-6, TNF-α, IL-8, NO synthase, MMP-9). Results: The analysis of the effectiveness of using different methods of approximation of the oral mucosa wound on inflammatory and immunological pa¬rameters showed that when using welding of the edges of the operated area using the EKVZ-300 “Patonmed” apparatus, we get positive results of laboratory indicators of inflammatory markers faster (leukocyte counts are normal on day 30, ESR, IL-1β – on the 14th day, TNF-α – on the 7th day, IL-6, IL-8, NO synthase, MMP-9 – on the 30th day), that is, healing in such patients is faster than in patients with wound closure with classic suture material or laser. Conclusions: When comparing the methods of approximation of postoperative oral mucosa wounds by different methods, based on the results of these inflammatory and immunological parameters, the best results were obtained when using electric welding of tissues. Further research and use of the proposed method will facilitate and shorten the rehabilitation period of patients after surgery.

Goal. To evaluate the effectiveness of the proposed method of cystectomy using electric welding on the basis of the obtained clinical and biochemical parameters. Materials and methods. Cystectomy was performed in 87 patients: 20 patients – 1 control group (classical surgical method), 28 patients – 2 control groups (cystectomy using laser technology) and 39 patients – the main group (cystectomy using electric welding). Results. The use of electric welding technology during cystectomy allowed to reduce and facilitate the postoperative period in patients of the main group up to 5 days in contrast to patients in other groups, in which symptoms of inflammation and pain were observed up to 14 days. Conclusions. The use of electric welding of tissues during cystectomy in the oral cavity allowed to achieve sterility of the operated area, reduce the intervention time, and due to the absence of foreign bodies in the wound to reduce and facilitate postoperative rehabilitation of patients. Key words: odontogenic cyst, cystectomy, electric welding of tissues, postoperative complications.

The article represents the results of experimental reproduction of a bone defect (removal of the lower masticatory tooth) of rabbits, followed by closure of the hole by various methods. Experimental animals were divided into 4 groups: 1 group – control, 2 group – suturing «Vikril», 3 group – joining the edges with a laser scalpel and 4 group – welding SOPR in the area of the removed tooth using an electric welding machine «Patonmed» EKVZ-300.After the experimental study, the results of clinical (hyperemia, edema, suture divergence, laser thermometry) and histological parameters were analyzed. The results showed an easier course and reduction of the postoperative period, as well as the formation of a strong weld, which eventually completely restores its structure, using the proposed technique of electric welding of fabrics, in contrast to the classic suture material and laser technology.That is, the above allows us to draw conclusions about the eff ectiveness of the proposed method of connecting the edges of the mucous membrane by electric welding of tissues during cystectomy in the oral cavity. The use of electric welding can reduce the time of surgery by 2 times compared to traditional methods, mainly by reducing the time spent on homeostasis. Also, a large number of methods and technologies for the treatment of odontogenic cysts, on the one hand, indicates a signifi cant development of this area, and on the other hand – the unsatisfactory results of their use. Therefore, further improvement and search for more modern technologies, including methods of approximation of postoperative wounds, in cystectomy operations remains one of the main directions in maxillofacial surgery.