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Methods: 164 hypertensive female patients (mean age 62,8 AE 7,1 yrs) with chronic renal failure (CRF) were enrolled in the study. Complete clinical data were collected (weight, height, waist circumference, BP). Blood sample and 24-h urin collection were obtained to meassure serum values of complete blood count, creatinine, glucose, total cholesterol, HDL and LDL cholesterol, tryglycerides, hsCRP, serum uric acid, sodium, potassium, creatinin clearance (CC) and microalbuminuria. Cardiac ultrasonography was performed to asses wall thicknes of the left ventricle. According to the CC value (60-90;30-60;15-30;<15 ml/min per 1,73m2) patients were assigned to four stages of CRF.Results: The prevalence of MS among the patients with CRF was 41,8%. In group of patients with MS significantly higher level of hsCRP (10,21 AE 2,82 mg/L vs. 5,24 AE 1,52 mg/L, p < 0,01) and serum uric acid (574 AE 153,06 umol/L vs. 366,03 AE 72,24umol/L, p < 0,01) was found compared to the group without MS.