Comprehensive results on the production of unidentified charged particles, π

Midrapidity production of π ± , K ± , and (p)p measured by the ALICE experiment at the CERN Large Hadron Collider, in Pb-Pb and inelastic pp collisions at √ s NN = 5.02 TeV, is presented. The invariant yields are measured over a wide transverse momentum (p T) range from hundreds of MeV/c up to 20 GeV/c. The results in Pb-Pb collisions are presented as a function of the collision centrality, in the range 0-90%. The comparison of the p T-integrated particle ratios, i.e., proton-to-pion (p/π) and kaon-to-pion (K/π) ratios, with similar measurements in Pb-Pb collisions at √ s NN = 2.76 TeV show no significant energy dependence. Blast-wave fits of the p T spectra indicate that in the most central collisions radial flow is slightly larger at 5.02 TeV with respect to 2.76 TeV. Particle ratios (p/π , K/π) as a function of p T show pronounced maxima at p T ≈ 3 GeV/c in central Pb-Pb collisions. At high p T , particle ratios at 5.02 TeV are similar to those measured in pp collisions at the same energy and in Pb-Pb collisions at √ s NN = 2.76 TeV. Using the pp reference spectra measured at the same collision energy of 5.02 TeV, the nuclear modification factors for the different particle species are derived. Within uncertainties, the nuclear modification factor is particle species independent for high p T and compatible with measurements at √ s NN = 2.76 TeV. The results are compared to state-of-the-art model calculations, which are found to describe the observed trends satisfactorily.

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We report the measured transverse momentum (p T) spectra of primary charged particles from pp, p-Pb and Pb-Pb collisions at a center-of-mass energy √ s NN = 5.02 TeV in the kinematic range of 0.15 < p T < 50 GeV/c and |η| < 0.8. A significant improvement of systematic uncertainties motivated the reanalysis of data in pp and Pb-Pb collisions at √ s NN = 2.76 TeV, as well as in p-Pb collisions at √ s NN = 5.02 TeV, which is also presented. Spectra from Pb-Pb collisions are presented in nine centrality intervals and are compared to a reference spectrum from pp collisions scaled by the number of binary nucleon-nucleon collisions. For central collisions, the p T spectra are suppressed by more than a factor of 7 around 6-7 GeV/c with a significant reduction in suppression towards higher momenta up to 30 GeV/c. The nuclear modification factor R pPb , constructed from the pp and p-Pb spectra measured at the same collision energy, is consistent with unity above 8 GeV/c. While the spectra in both pp and Pb-Pb collisions are substantially harder at √ s NN = 5.02 TeV compared to 2.76 TeV, the nuclear modification factors show no significant collision energy dependence. The obtained results should provide further constraints on the parton energy loss calculations to determine the transport properties of the hot and dense QCD matter.

Computer-aided detection and diagnosis (CAD) systems are increasingly being used as an aid by clinicians for detection and interpretation of diseases. Computer-aided detection systems mark regions of an image that may reveal specific abnormalities and are used to alert clinicians to these regions during image interpretation. Computer-aided diagnosis systems provide an assessment of a disease using image-based information alone or in combination with other relevant diagnostic data and are used by clinicians as a decision support in developing their diagnoses. While CAD systems are commercially available, standardized approaches for evaluating and reporting their performance have not yet been fully formalized in the literature or in a standardization effort. This deficiency has led to difficulty in the comparison of CAD devices and in understanding how the reported performance might translate into clinical practice. To address these important issues, the American Association of Physicists in Medicine (AAPM) formed the Computer Aided Detection in Diagnostic Imaging Subcommittee (CADSC), in part, to develop recommendations on approaches for assessing CAD system performance. The purpose of this paper is to convey the opinions of the AAPM CADSC members and to stimulate the development of consensus approaches and "best practices" for evaluating CAD systems. Both the assessment of a standalone CAD system and the evaluation of the impact of CAD on end-users are discussed. It is hoped that awareness of these important evaluation elements and the CADSC recommendations will lead to further development of structured guidelines for CAD performance assessment. Proper assessment of CAD system performance is expected to increase the understanding of a CAD system's effectiveness and limitations, which is expected to stimulate further research and development efforts on CAD technologies, reduce problems due to improper use, and eventually improve the utility and efficacy of CAD in clinical practice.