NPDS without or with an autologous scleral implant is a safe procedure reducing the IOP significantly, but probably not sufficient when an IOP below 16 mmHg is required. We found no statistically significant difference between the two groups.

Acknowledgements:We thank the patients with SCA7, in particular the index case.Abstract A 22-year-old woman (index case) presented at the department of ophthalmology with progressive visual loss for the past 3 years. Ophthalmological examination revealed a visual acuity of 20/100 in each eye. At funduscopy, a dull macular reflex was noted. Family history revealed spinocerebellar ataxia type 7 (SCA7) in three generations. We describe the ophthalmological findings in this family. Insidious visual problems can be the presenting sign of spinocerebellar ataxia type 7. In examining a negative family history, the diagnosis can be very difficult.