What are the novel findings of this work?Our study has developed further a competing-risks model for the prediction of a small-for-gestational-age (SGA) neonate using maternal demographic characteristics and medical history, third-trimester fetal biometry, uterine artery pulsatility index and placental growth factor at 35−37 weeks' gestation, which has shown superior performance compared with estimated-fetal-weight percentile cut-offs.
What are the clinical implications of this work?Application of a competing-risks model at 36 weeks' gestation provides effective risk stratification for a SGA neonate, in contrast to the traditional method of estimated-fetal-weight percentile cut-off.
What are the novel findings of this work?In pregnancies conceived via in-vitro fertilization (IVF), compared with those conceived spontaneously, the fetal heart was globular and left ventricular systolic function assessed by speckle tracking was mildly reduced. These differences were independent of the type of embryo transfer (fresh or frozen).
What are the clinical implications of this work?In IVF pregnancies, compared with those conceived spontaneously, there is evidence of fetal cardiac remodeling at midgestation, which is not related to the use of fresh or frozen embryo transfer or changes in placental perfusion and function. These findings suggest an independent effect of IVF on the fetal heart.
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