This study aims at providing a framework to find out best agro-food practices and foster their spreading to European actors operating in Short Food Supply Chain (SFSC). Quick knowledge circulation allows a reduction of asymmetric information among such operators. These latter frequently imply an excessive level of transactional costs that negatively affect farms economic sustainability. Hence, reduction of costs is an important priority. The methodological approach is carried out within the SKIN project, analyzing metrics parameters to assess SFSC economic sustainability. It will create local hubs to collect knowledge from each European area where stakeholders operate, through the identification of adequate regional nodes, connected among themselves. Network will enable a real knowledge transfer and innovation uptake. Lastly, the network will be exploited to enhance the added value of involved farms.