Generally seaweeds are an essential source in the field of pharmaceutical industry because of their bioactive metabolites. Life threatening diseases like acquired immuno defieciency syndrome (AIDS), cancer and other infectious diseases can be trated with the constituents present in the Gracilaria species. This paper deals with a compilation of the literature for Gracilaria corticata algae extracts from the beginning of this century with its pharmacological benefits and recognizes opportunities for forthcoming research.
Clitoria ternatea is a vigorous, herbaceous perennial legume that belongs to the Fabaceae family. All parts of the plant are used in the preparations of Ayurvedic drugs. It is an astringent, an aphrodisiac, a rejuvenator, and a brain tonic. It also has anti-inflammatory, analgesic, and antipyretic properties. Baidyanath Shankapushpi, which contains extracts of herbs such as C. ternatea, Bacopa monnieri, Withania somnifera and Asparagus racemosus, is clinically administered for memory improvement, blood purification and to improve digestion. However, its neuroprotective effect has not been reported so far. In the present study, the neuroprotective effect of C. ternatea root (CTR) extract on hippocampal CA3 neurons was investigated. Three-month-old albino mice were divided into four groups. Group I was the normal control, group II was the saline control, group III was the stress group, and group IV was the stress + CTR-treated group. Group-III mice were stressed in a wire mesh restrainer for 6 hours/day for 6 weeks. Grou-IV mice were also stressed like group III, but received CTR extract orally throughout the stress period. After 6 weeks, their brain was removed, and their hippocampi were dissected and processed for Golgi staining. The hippocampal neurons were traced using a camera lucida focused at 400x magnification. The Sholl concentric circle method was used to quantify the dendrites. The results showed a decrease in the number of dendritic branching points and of dendritic intersections in the stressed group. On the other hand, there was an increase in the number of dendritic branching points and of dendritic intersections of hippocampal CA3 neurons in group IV, which was subjected to restraint stress and was treated with the CTR extract. The results showed that the oral administration of CTR significantly increased the dendritic branching points and the dendritic intersections of hippocampal CA3 neurons.
The Brachial artery is a continuation of the axillary artery, from the inferior border of the tendon of teres major to the neck of the radius, terminating into radial and ulnar arteries just a cm distal to the elbow joint. Unlike veins, variations in the arteries are comparatively less common. Anatomical variations of the brachial artery occur in almost 20% of the cases and are commonly found during routine dissection or clinical practice. To observe the variations in the course and termination of brachial artery by dissection and computed tomography (CT) angiography methods. The present study was conducted on 40 upper limbs each in the department of Anatomy & Radiology of JSS Medical College and Hospital, Mysuru. The brachial artery was traced from origin to termination and variations were noted and photographed. Patients who were undergoing CT angiography of the upper limbs in JSS Hospital were included in the study. Variations noted and compared with the dissection method. In the present study, normal patterns of the brachial arterial course and termination were observed in 31 specimens. The remaining 9 specimens showed variant course and termination in the brachial artery like an unusually tortuous superficial brachial artery, superficial brachio-ulnar artery and brachio-radial artery. CT angiography showed 6 variations and a tortuous brachial artery. A detailed description of the vascular pattern of upper limbs especially variations in their origin and termination is of extreme importance in clinical practice. The knowledge of these variations is important for catheterization, graft harvesting, arteriovenous fistula creation, shunt application and astrup examination.
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