A 59-year-old female with a cystic fibroepithelioma of Pinkus is presented. The clinical and histopathological features of this unusual variant of basal cell carcinoma are discussed.
African American (AA) and Hispanic/Latina (HL) women report lower rates of physical activity (PA) and poorer dietary habits compared to their white counterparts. Religiosity can act as a protective factor for health; however, the relationship between religiosity, PA, and diet is unclear. This study aimed to investigate the influence of religiosity on PA and fruit and vegetable (FV) and fat consumption in minority women. Health is Power (HIP) was a 6-month intervention where participants (AA: 63%; HL: 37%) were randomized to a PA or FV group. Questionnaires assessed religiosity at baseline and PA, FV and fat consumption at baseline and post-intervention. Hierarchical linear regression models were used to investigate religiosity as a predictor of change in PA, FV and fat, while controlling for demographics. AA women had significantly higher religiosity scores (M = 44.15, SD = 10.66) compared to H/L women (M = 35.11, SD = 12.82; t(251) = 5.86, p < 0.001). Across both groups, PA increased by 15%, FV intake increased by 27%, and consumption of calories by fat decreased by 5%. Religiosity was not a significant predictor of PA or diet (p < 0.05). The results of this study found no association between religiosity and change in PA and diet. More longitudinal studies are needed to explore the role of religiosity in the health of minority women.
The histogenesis of atypical fibroxanthoma (AFX) and its relationship to malignant fibrous histiocytoma (MFH) are a subject of controversy. Many investigators have proposed that AFX may represent a reactive process, while others contend that it is a true fibrohistiocytic neoplasm, closely related to MFH. In an attempt to determine whether biologic differences between AFX and MFH may be accounted for at the cellular DNA level, we performed ploidy analysis on 14 cases of AFX by flow cytometry and compared our results with previously reported DNA analyses of MFH. Thirteen of the 14 lesions demonstrated diploid distribution of nuclear DNA, and only 1 case had an aneuploid population. This contrasts with prior data on MFH, the vast majority of which are aneuploid. Our results suggest that, despite histologic similarities, AFX may be distinguished from MFH on the basis of DNA content. These findings may be significant in understanding the biologic behavior of AFX.
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