Aims-To describe the clinical features of patients with a history of recurrent corneal epithelial erosion who develop acute corneal infiltration. Methods-The records were reviewed of patients who had previously been examined and treated for recurrent corneal epithelial erosion and who presented again with signs suggestive of a microbial keratitis. Results-11 patients were described; one patient presented with similar signs on two occasions. There was typically a paracentral epithelial defect >2 mm in diameter with an associated stromal infiltrate and an intense anterior uveitis. Three patients had a hypopyon, and four developed a subepithelial ring infiltrate. Samples were taken for microscopy and bacterial culture, with a positive isolate from two of 12 episodes (16%). Treatment with topical antibiotics and topical corticosteroid resulted in rapid reepithelialisation and a reduction of inflammation. There was good visual outcome for all eyes, with a recurrence or symptoms of epithelial erosion in only one eye after a mean follow up period of 18 months. Conclusions-Corneal infiltrates are an uncommon complication of recurrent corneal epithelial erosion. Despite the intensity of the infiltration the majority are culture negative using established techniques. There is typically rapid resolution and a good visual outcome, with a tendency for the episode to mark the end of further symptoms of epithelial erosion. (Br J Ophthalmol 1997;81:537-540) Recurrent corneal erosion (RCE) can develop after mechanical injury, as a complication of chronic ocular surface disease, or as a result of inherited dystrophies of the epithelial basement membrane or stroma.

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Aims-The choice of a prophylactic antibiotic for cataract surgery is dependent on its antibacterial activity and tissue pen-

Aims-To describe the clinical features of patients with a history of recurrent corneal epithelial erosion who develop acute corneal infiltration. Methods-The records were reviewed of patients who had previously been examined and treated for recurrent corneal epithelial erosion and who presented again with signs suggestive of a microbial keratitis. Results-11 patients were described; one patient presented with similar signs on two occasions. There was typically a paracentral epithelial defect >2 mm in diameter with an associated stromal infiltrate and an intense anterior uveitis. Three patients had a hypopyon, and four developed a subepithelial ring infiltrate. Samples were taken for microscopy and bacterial culture, with a positive isolate from two of 12 episodes (16%). Treatment with topical antibiotics and topical corticosteroid resulted in rapid reepithelialisation and a reduction of inflammation. There was good visual outcome for all eyes, with a recurrence or symptoms of epithelial erosion in only one eye after a mean follow up period of 18 months. Conclusions-Corneal infiltrates are an uncommon complication of recurrent corneal epithelial erosion. Despite the intensity of the infiltration the majority are culture negative using established techniques. There is typically rapid resolution and a good visual outcome, with a tendency for the episode to mark the end of further symptoms of epithelial erosion. (Br J Ophthalmol 1997;81:537-540) Recurrent corneal erosion (RCE) can develop after mechanical injury, as a complication of chronic ocular surface disease, or as a result of inherited dystrophies of the epithelial basement membrane or stroma.

The assessment of the topography of the cornea is an important modality in the management of surgical procedures complicated by astigmatism. Additionally, the outcome of corneal refractive surgery is often best illustrated by photokeratoscopy. Currently available photokeratoscopes suffer from a number of deficiencies that include (i) the lack of topographic detail from the central cornea, (ii) the difficulty in transporting these units, (iii) the cost of such units. A photokeratoscope which addresses these shortcomings is described.