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Breast cancer in women is amongst the most significant concerns from time immemorial in the field of oncology. This study proposes an anticancerous polymeric material based on an electroactive substituted polyaniline blend, poly(2-aminobenzoic acid)-blend-Aloe vera (PABA/AV) synthesized by the emulsion polymerization method. The structural, thermal, and morphological characteristics determined using FT-IR and UV-Visible Spectroscopy, XRD, TGA, DTA, and SEM-EDX validated the thermally stable, semi-crystalline, emeraldine salt structure. The material is semi-conducting, and the electrical conductivity measured is 1.86 × 10−3 S/cm. It shows bactericidal efficacy against Enterococcus faecalis at a minimum inhibitory and minimum bactericidal concentration of 50 μg/mL. The radical cations in the emeraldine polymer chain reduce the 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical and exhibit a significant % of DPPH scavenging (89.85%) at 20 μL. The polymer blend is active against the human breast cancer cell line MDA-MB-231 and causes 78.65% cytotoxicity at a concentration of 125 μg/mL. The synergistic effect of the ancient healing Aloe vera plant and the electroactive biocompatible poly(2-aminobenzoic acid) certainly opens up new developments in the field of cancer therapy.

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This work evaluates the application of interfacially polymerized poly(2-chloroaniline)-nanocompositesilica (P2ClAni-SiO2), a composite material based on substituted conducting polymer, poly(2-chloroaniline) (P2ClAni) in which silica nanoparticles with varying weight percentages act as fillers. The nanocomposites were characterized by FTIR spectroscopy, XRD, TGA and DSC analysis. The electrochemical characterization of P2ClAni and P2ClAni-SiO2 (10 wt.%) were investigated by cyclic voltammetry, impedance spectroscopy and galvano-static cycling electrochemical measurements. The cyclic voltammogram studies showed broad redox peaks, which correspond to reversibility in transition of leucoemeraldine to emeraldine form of polyaniline. The charge transfer between electrolyte and electrode was represented in the form of Nyquist plot. The galvanostatic cycling test of P2ClAni and P2ClAni-SiO2 showed a discharge capacity of 44.3 mAh g-1 and 69 mAh g-1 for 5 cycles, respectively. P2ClAni-SiO2 composite shows good electrochemical properties and cycling stability compared to P2ClAni. The chlorosubstituted polyaniline with silica demonstrate to be an anode material in lithium ion batteries.