No abstract

Green synthesis is considered to be eco-friendly approach in comparison to chemical mediated synthesis and hence the study demonstrates facile Nyctanthes arbortristis mediated phyto-synthesis of biocompatible yttrium oxide (Y2O3) nanoparticles. X-ray diffraction (XRD) and Fourier Transform Infrared Spectroscopy (FTIR) were employed to confirm the formation of cubic Y2O3 nanoparticles. Further, the interaction of Y2O3 with calf thymus-DNA were scrutinized by UV-visible, fluorescence spectroscopy and agarose gel electrophoresis techniques and the results suggested the stabilization of CT-DNA by the biosynthesized Y2O3. Also, the synthesized Y2O3 does not exhibit any toxicity in SK-MEL, human melanoma cell lines. Further, the studies on antifungal activities of Y2O3 nanoparticles revealed significant inhibitory effects on the growth of plant pathogen Exserohilum rostratum causing Exserohilum leaf blight in pearl millet. Hence, the findings deliver the foundation for furtherbiological research investigations of Y2O3 and its application in phytopathogen control.