Russian Society of Cardiology, National Society of Preventive Cardiology

Our objective was to assess the relationship between coronary artery calcification and outcomes of percutaneous transluminal coronary angioplasty (PTCA). Electron beam computed tomography (EBCT) was performed in 80 patients with coronary artery disease (CAD) who underwent PTCA. The calcium score in each coronary artery vessel was estimated (in Agatston units) and compared with the occurrence of complications and restenosis. Angioplasty had been performed in 96 coronary artery segments with stenosis in 80 patients. The average calcium score in the unsuccessful PTCA segments was significantly higher than in ones with successful results. For complications these values were 65.0±79.9 and 27.0±44.7, respectively (p=0.02), and for restenosis 63.9±87.9 and 27.3±41.3, respectively (p=0.03). Applying receiver operating characteristics analysis we determined sensitivity and specificity of EBCT for forecasting complications and restenosis. The best cut-off value of calcium score in segment of PTCA for prediction of restenosis was 27 (sensitivity 73%, specificity 67%), and for prediction of complications 29 (sensitivity 80%, specificity 74%). Coronary segments with extensive calcification were not optimal target lesions for PTCA. Analysis of coronary calcium score should be taken into consideration during planning of endovascular coronary interventions.Relationships between coronary calcification detected at electron beam computed tomography and percutaneous transluminal coronary angioplasty results in coronary artery disease patients

analysis of diagnostic performance of coronary computed tomography angiography, computed tomography perfusion, and computed tomography-fractional flow reserve in functional myocardial ischemia assessment versus invasive fractional flow reserve.

ель исследования. Тестирование (проверка) методики неинвазивного определения фракционного резерва кровотока (ФРК) на основании данных, полученных при проведении компьютерной томографической ангиографии (КТА) коронарных артерий. Результаты. Гидродинамический расчет кровотока в коронарной артерии позволил получить оценку ФРК с отклонением от инвазивно измеренных значений ФРК равным или меньшим 7%. Заключение. Продемонстрирован научный и клинический потенциал предложенной ранее методологии неинвазивного определения ФРК по результатам КТА для оценки функциональной значимости пограничных стенозов в коронарных артериях. Ключевые слова: фракционный резерв кровотока (ФРК), коронарные артерии, компьютерная томографическая ангиография (КТА), триангуляция поверхности, математическое моделирование.