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alve selection in the patient with a small aortic root remains a difficult decision for cardiac surgeons. Use of smaller stented porcine tissue valves in these patients may result in high gradients and low effective orifice areas. 1,2 In some cases, there may be prosthesis-patient mismatch, 3 which can result in persistent left ventricular hypertrophy after valve replacement and has been reported in up to 52% of patients. 4 Jin and colleagues 5 found no significant regression of left ventricular hypertrophy in patients after implantation of either stented tissue valves or mechanical valves, although patients receiving unstented tissue valves and homografts did demonstrate significant regression.Recognition of the potential importance of prosthesis-patient mismatch has led to interest in developing valve substitutes with improved hemodynamics. Although much of the recent literature has focused on stentless tissue valves, more traditional valve designs have also evolved to meet this challenge. The St Jude Medical HP (High Performance) valve was designed to allow supra-annular placement of the valve through modification of the sewing ring on a standard St Jude Medical valve. This allows a valve approximately one size larger to be inserted in the same size aortic root. Intuitively, one would expect this valve to have lower pressure gradients possibly resulting in better remodeling of the ventricle and more complete regression of hypertrophy after valve replacement than the standard cuff (SC) St Jude Medical valve. However, evidence for an improvement in hemodynamics with the HP valve has been lacking.In this issue of the Journal, Vitale and coworkers 6 report a randomized, multicenter trial comparing the postoperative and 6-month hemodynamics between the St Jude Medical HP and SC valves. The results are interesting on several levels. When HP and SC valves were compared at 6 months, both peak and mean pressure gradients were lower in the 21-mm and 23-mm HP valves than in the SC valves of the same size. However, effective orifice area did not differ significantly between SC and HP valves. A possible explanation for this finding lies in the greater cardiac output in the patients with SC valves in this series, which makes it difficult to draw definitive conclusions about the hemodynamic superiority of HP over SC valves. At 6 months, both the 21-mm and 23-mm HP valves demonstrated similarly low gradients (mean gradients of 18.8 and 14.9 mm Hg, respectively) and good effective orifice areas (1.56 cm 2 and 1.60 cm 2 , respectively). These observations suggest that aortic root enlargement procedures may not be needed to upgrade from a 21-mm HP valve to a 23-mm HP valve since little additional hemodynamic benefit accrues. Vitale and coworkers also examined the prevalence of postoperative patient-prosthesis mismatch. In contrast to the high prevalence in prior reports noted above, no patient in this series had patient-prosthesis mismatch according to an effective area index less than 0.9 cm 2 /m 2 , slightly stricter criteria ...

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