Background: Many donor organs come from youths involved in alcohol-related accidental death. The use of cardiac allografts for transplantation from donors after acute poisoning is still under discussion while acute ethanol intoxication is associated with myocardial functional and morphological changes. The aims of this work were 1) to evaluate in rats the time-course cardiac effects of acute ethanol-exposure and 2) to explore how its abuse by donors might affect recipients in cardiac pump function after transplantation.

Syntheses of New Phosphono Analogues of Pantetheine Derivatives.-The phosphono analogues (III) and (V) of pantothenate 4'-and pantetheine 4'-(dibenzyl phosphate), resp., are synthesized as intermediates for the preparation of a coenzyme-A phosphono analogue. Furthermore, the phosphono analogues (IX) and (X) of oxapantetheine are prepared. -(NEIDLEIN, R.; LI, S.; Helv.

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Syntheses of 1,2,4-Oxadiazole Substituted Pyrazole, Isoxazole and Pyrimidine Heterocycles.-The preparation of title compounds like (II), (V) and (VIII) is reported. The structure of product (IIa) is established by X-ray analysis. -(NEIDLEIN, R.; LI, S.; J.

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