Green synthesis of silver nanoparticles (AgNPs) is non-toxic, rabid and ecofriendly than commonly used physicochemical methods. This study focuses on synthesis, characterization, hepatoprotective effect and antioxidant activity of AgNPs synthesizes from Cymbopogan Citratus (Lemongrass). Silver nanoparticles were formed within 30 minutes by heating to 80 o C magnetic stirrer using aqueous solution of AgNO3 (0.1 N) with fresh leaves methanolic extract of Cymbopogan Citratus. The synthesized silver nanoparticles were characterized by using UV-visible spectrophotometer analysis and transmission electron microscope (TEM). The antioxidant activity of nanoparticles were determined in vitro by reducing power, total antioxidant capacity and free radical scavenging activity by (DPPH). and experimental study was designed to evaluate the antioxidant activity and hepatoprotective effect of silver nanoparticeles, methanolic extract and essential oil comparing with vitamin E. Results: (UV-Vis) spectrum of synthesized AgNPs shows a peak at 412 nm and the size of silver nanaoparticels was 13.5 nm by (TEM).Silver nanoparticles showed potent hepatoprotective effect and antioxidant activity in both in vitro and in vivo methods.

The present work aims to study the potential effect of Moringa Oleiferato (MO) seed oil and seed ethanol extract to give more protection against hyperlipidemia . Thirty male albino rats were used over 30 days period. The animals were divided into (5) groups, wherein groups number (1) represent control which were fed basal diet, while group number (2) was received high fat diet to serve as hyperlipidemic group. Other three groups allowed to feed high fat diet supplemented with seed oil , seed ethanol extract and atrovastatin, group number (3) treated simultaneously with moringa seed oil, fourth group treated with moringa seed ethanol extract while the last group treated with atrovastatin. At the end of the experimental period, blood samples were collected to determine lipid profile and determine the kidney functions include urea nitrogen and creatinine. Also liver was removed surgically for histopathological observation. From the obtained results we concluded that group of rats fed on high fat diet were considered as a major risk factor for hyperlipidemia disease. Our results could be summarized that moringa seed oil and moringa seed ethanol extract were considered the best for causing a reduction of TC, TG and LDL . Also, kidney function has been improved and there were significant reduction urea and creatinine than that of positive control group. It could be concluded that moringa seed oil and moringa seed ethanol extract under study are useful for the treatment of hyperlipidemia.

The present study was designed to investigate the chemical composition of Swietenia mahagoni seeds , identification of phenolic compounds in acetone extract in mahagoni seeds, studying the fatty acids composition, and evaluation of mahagoni extracts and oil on the glucose level of diabetes rats. The chemical composition of seeds were moisture (3.6 %), crude fiber (14 %), ash (3%), crude protein (13 %), crude fat (7.4 %) and total carbohydrate (62.6 %). The fatty acids composition were lignoceric acid (C24) 38.23% followed by stearic acid (C18) 35.69%, meanwhile the unsaturated fatty acid was linoleic acid (C18:2), which accounted for ( 26.08 %). The phenolic compound in acetone extract showed that menthol and nerolidol are the major phenolic ( 12.32 and 10.06 % respectively ). Ttreatment with Swietenia mahagoni seed extracts and oil decreased significantly glucose level , also decreased significantly GOT , GPT , ALP , urea , creatinine and malondialdehyde level as compared with hyperglycemic group .

Chemical composition of milk thistle seed flour )MTSF) and turmeric (T)were investigated, for milk thistle seed flour, moisture (8.0%), protein (13.0 %), carbohydrates (27.55%), crude lipid (15.0%), ash (10.45%), and crude fiber (26.0%), while turmeric has moisture (8.1%) , protein (9.3 %), carbohydrates (57%), crude lipid (17.0%), ash (6.0%) and crude fiber (2.6%). For total phenol, the highest value in turmeric (11.57mg GAE/g) while milk thistle seed flour (3.39 mg GAE/g)) also total flavonoid for turmeric (4.9mg) while and in milk thistle seed flour (2.34mg). DPPH for milk thistle recorded the highest percent of (FRSA) 98.5 % and turmeric recorded lowest present 82.2% in concentration 100 µg/ml. Reducing power for milk thistle recorded 0.651 but turmeric (T) recorded 0.502 in concentration 100 µg/ml . The identification of phenolic compounds for plant extracts were investigated by HPLC ,the highest content in milk thistle seed flour (MTSF) was Benzoic acid (103.33 ppm) while the lowest content was Caffeine(1.07 ppm) but in turmeric(T) the highest content was Benzoic acid (208.41 ppm), while the lowest content was quercitin (3.08 ppm).The level of plasma aspartate aminotransferase (AST) , alanine aminotransferase (ALT) , alkaline phosphatase (ALP) , total bilirubin , total protein and albumin and plasma antioxidant state SOD , CAT, GPx and MDA were determined to assay hepatotoxicity.

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