Background: Dysmenorrhea is a common gynaecological condition which causes physical pain, affects mental well-being and quality of life. The aim of the present study was to evaluate the prevalence, severity and the treatment patterns of primary dysmenorrhea among female medical students.Methods: The present study was a prospective, questionnaire based study conducted during March-April 2020 at KIMS, Koppal. The willing participants were given a time period of 30 minutes to fill the questionnaire.Results: Among the total of 211 female medical students, 180 students were suffering from dysmenorrhea. Almost 78.3% of those suffering from dysmenorrhea belonged to the age group of 19-21 years. Most of the students suffering from dysmenorrhea achieved menarche at the age of 13-14 years.  A majority (48.8%)  of the dysmenorrhic females had dysmenorrhea of mild degree. 73.8% of dysmenorrhic females did not seek any medical advice for the management of the symptoms of dysmenorrhea. 76 (42.2%) of the dysmenorrhic participant females missed their classes due to the symptoms of dysmenorrhea. The most favoured drug for the management of the symptoms of dysmenorrhea was the combination of mefenamic acid and dicyclomine (56.8%). 56.6% of the subjects utilized pharmacological measures, while the rest 43.3% utilized non-pharmacological measures for the relief from the symptoms of dysmenorrhea.Conclusions: The present study recognized that dysmenorrhea is a common menstrual disorder among young females. There should be an effort at mass education of the young females regarding the management of dysmenorrhea.

Context: COVID-19 is known to cause extrapulmonary manifestations, including gastrointestinal and abnormal liver functions. Multiple mechanisms have been proposed to explain the pathobiology of liver damage: ACE2 receptor cholangiocytes mediated systemic inflammation, cytokine storm, hyperinflammation, and hypoxic changes. This was a cross-sectional study done in Department of General Medicine,JJM Medical College Davangere between July and September 2020 of patients falling under Category B and Category C. Materials and Methods: The aim is to describe the clinical characteristics in patients of COVID-19 and investigate the gender difference with particular regard to liver impairment.Confirmation of COVID-19 positivity was based on RT-PCR for SARS-CoV-2 RNA. Laboratory investigations and clinical data was analyzed using SPSS Statistics 27. Results: The final study population consisted of 116 patients. On performing the Mann Whitney U test, adjusted P values reveal a significant difference in ALT ( P = 0.0348), total bilirubin ( P = 0.0012) and direct bilirubin ( P = 0.0024). The degree of hypoalbuminemia in males was significantly higher than in females ( P = 0.0075). Other biochemical parameters, however, did not show significant difference amongst patients based on gender. Acute kidney injury was the most prevalent condition, present in 67.2% of the patients. Other co-morbidities were diabetes mellites, chronic liver disease, hypertension, hepatitis B and C, and hypothyroidism. Conclusion: Ultrasonography of the abdomen is an essential investigation for all patients testing positive for COVID-19. Pre-existing disease may aggravate the viral hepatic injury, thereby worsening the clinical outcome. The profiles of liver toxicity of the drugs used in the treatment of COVID-19 also warrant watchful monitoring of liver function.

Coronavirus infection is a transmissible disease. It was first described in China in December, 2019. It has been said to have a person-to-person transmission after prolonged and unprotected exposure. Patients with a potential SARS-CoV-2 exposure present with symptoms of low-grade pyrexia, dry cough, or shortness of breath. People with these symptoms should contact health-care providers before seeking medical intervention so that appropriate preventive actions may be implemented. Health-care facilities should rapidly isolate suspected individuals and notify local health departments for support involved in performing laboratory tests and efforts in containment. The present article describes the nature of virus, method of detection, and its mode of transmission.

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