Osteoradionecrosis (ORN) defines exposed irradiated bone, which fails to heal over a period of 3-6 months without evidence of residual or recurrent tumor. It is a long term and serious complication of therapeutic radiotherapy for head and neck cancer. The pathogenesis of ORN has been proposed relating it to a fibroatrophic mechanism including free radical formation, endothelial dysfunction, inflammation, microvascular thrombosis leading to bone and tissue necrosis. Risk factors mainly include radiation related risk factors, surgery, tobacco and alcohol abuse. Removing of diseased teeth after radiotherapy is generally considered the main risk factor in ORN. Prevention of ORN is based on the preventive extractions of decayed or periodontally compromised teeth before radiotherapy. Based on the clinical staging various therapeutic protocols have been suggested. We here report a case of Bilateral mandibular ORN with discussion of clinical features, pathogenesis, preventive measures, and management of ORN.

The organo-phosphorus compound Dipterext (trichlorphon; OO-dimethyl-2,2,2,-trichlorethyl phosphonate) has attracted considerable attention during the past few years. Besides its use as an insecticide, an attempt has been made to employ this substance for the treatment of intestinal parasites (Beheyt, Lebrun, Cerf, Dierickx, and Degroote, 1961 ; Cerf, Lebrun, and Dierickx, 1962). Schistosomiasis is a very common condition in the United Arab Republic and a simplified course of treatment given by mouth would be a great improvement on the treatment in use. Hence a trial experiment was carried out to evaluate the efficacy of Dipterex in treating bilharziasis. Material Ten male patients suffering from active urinary bilharziasis were admitted to the

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