Acinetobacter infections are highly prevalent in the ICU, with medical patients being more susceptible to lung infections, particularly late-onset VAP. The early and appropriate selection of antibiotics is the most important determinant of survival among these patients.

Background: Tuberculosis of the central nervous system (CNS) is a highly devastating form of tuberculosis, which, even in the setting of appropriate antitubercular therapy, leads to unacceptable levels of morbidity and mortality. Aim: To study the various clinical presentations of Central Nervous System Tuberculosis, complication, morbidity and mortality and various types of treatment modalities and their outcome. Methods: 240 patients with CNS-TB were included in the study. Detail history of any prior antituberculous treatment, their duration, and regimen was enquired. A thorough general examination was made including pulse, blood pressure, skeletal system, skin, and eye. Nervous system was examined in detail looking for signs of meningeal irritation and focal neurological deficit. Results: 19 patients (63.3%) were tuberculous meningitis, 7 patients (28.3%) were tuberculoma of the brain, 2 patients (6.6%) were tuberculous Arachnoiditis, and 2 patients were Pott's paraplegia (6.6%). In TBM patients, who had presented as 'Aseptic Meningitis' form had food recovery without any sequelae. In this series, complete recovery was 66.6% mortality was 13.3% and sequelae in 20%. Patients treated with Pyrazinamide had its full effect during first 2 months of treatment and had a good recovery. Conclusion: Timely diagnosis of central nervous system tuberculosis is of key importance because delayed treatment is associated with higher morbidity and mortality.