Introduction: Laparoscopic cholecystectomy is a gold standard surgical procedure in post-operative pain recovery time. Though it is associated with lesser post-op pain than open cholecystectomy, few patients still experience pain. Pain relief is an important goal of any surgery. Administration of local anaesthetic either during surgery is a method of reducing post-op pain. To Compare the effect of intraperitoneal Aim: instillation of 0.5% bupivacaine with adrenaline and without intraperitoneal instillation of 0.5% bupivacaine with adrenaline for post-operative analgesia in laparoscopic cholecystectomy. A total of 120 participants we Materials & Methods: re considered for this study with 60 participant receiving bupivacaine and other 60 receiving normal saline. VAS/VRS score is measured at 2, 4, 6, 12 & 24 hours after surgery for each group. Results: From the results, we found signicant differences in the mean scores of study group and placebo group. The patients who were given bupivacaine were found to have reduced pain. Conclusion: In our study, we found that bupivacaine reduces postoperative pain. We conclude that the intraperitoneal instillation of bupivacaine is a safe and effective method for providing postoperative analgesia without signicant side effects.

Introduction: Various techniques and medications are employed to lessen postoperative discomfort. Present study aimed to assess the efcacy of pre-operative tramadol suppository administration for the management of post-operative pain in patients undergoing surgery under spinal anaesthesia, requirement of analgesia and duration of hospital stay. Material & Method: The present comparative study with patients presenting to the department of General Surgery, AVMCH who were posted for elective surgeries & with no evidence/signs of inammation/infection consenting were included in the study. Patients were grouped based on utility of tramadol suppository, cases were with administration of rectal suppository and control group was with no pre-operative administration of rectal suppository. The patients were assessed for the post-operative pain at different point of time, mean duration of hospital stay and any side effects like nausea, vomiting between the groups. Results: Total 152 patients included in the study, with mean age of 47.57yrs. The pain score was signicantly lower among the cases compared to control at 1st hr, 6th hr, 12th hr and 24th hr post-operative period. (p<0.05) There was signicant shorter duration of hospital stay among the cases (2.3days) compared to controls (3.2days).(p<0.05) Conclusion: A signicant pain management in post-operative period with the utility of tramadol suppository administration compared to the patients without suppository