Obtaining bilateral balance of removable complete denture prostheses is the occlusal goal of the restorative dentist or prosthodontist. Despite our best clinical efforts, and the using of advanced mechanical devices like semi-adjustable articulators and face bow transfer mounting of dental casts, it is a struggle to provide accurate occlusal force balance. Some of the advocated reasons for the clinical difficulty of obtaining reliable occlusal balance are that stone casts lack soft tissue resiliency, and articulators only approximate human occlusal functional movements. However, modern technology offers clinicians a digital answer to this clinical force balance problem. It is known as computerized occlusal analysis. The T-Scan III system can be employed with complete removable denture prostheses to perform computer-guided occlusal force-finishing corrective adjustments that measurably improve the installed prosthetic occlusal balance.
Dental materials for permanent restorations are manufactured with the intent to be stable and insoluble, but they do not fully achieve this goal. The amount of dissolved components is small and their detection sometimes requires sophisticated analytical equipment. The minute amounts of components that leach out of permanent dental restorative materials are most unlikely to cause toxic reactions, locally or systemically. Reliable research information using robust methodology is thus needed to clarify the various safety issues and frequency of adverse reactions in general dentistry, including prosthodontic treatment.
The objective of the study was to detect the presence of fimH gene among the drug resistanst strains of Acinetobacter baumannii. fimH gene was found to be associated with a catch bond mechanism which led to better evolution of biofilm formation. Since there are not many studies done with this gene it would be a timely investigation and this study mainly aims in molecular characterization of fimH gene among clinical isolates of A. baumannii. Semi quantitative bio adherent assay was done by the multidrug resistant strains of A. baumannii to find the formation of biofilm. The DNA was extracted with the help of kit and PCR was performed for amplification. Pearson correlation analysis was done to find the existing correlation between the fimH gene and MDR strains of A. baumannii with significant p-value of (<0.05). From the screened 73 genomes of MDR A. baumannii 6.8% showed positive amplicons for the fimH gene which were related to biofilm and porin formation (Fig. 1). Correlation of its existence was high in beta lactamase (100%), cephems (100%), folate (100%) resistant strains, followed by aminoglycosides (80%), carbapenems (60%) and fluoroquinolones (60%) and efflux pumps (20%). In Spite of various measures undertaken to prevent the disease, the prevalence of the pathogen is multiplying. The current study recorded the presence of fimHgene (6.8%) among the clinical isolates of A.baumannii. This gene can be used as a target to develop new drugs and vaccines to combat the menace of A.baumannii infection.
It is the god given right of every human being to appear human. Few areas of dentistry offer more challenges to the technical skills or greater satisfaction for the successful rehabilitation of function and esthetics in the patient with gross anatomic defects and deformities of the maxillofacial region. Although remarkable advances in the surgical management of oral and facial defects, but cannot be satisfactorily repaired by plastic surgery alone. Hence, the demand for maxillofacial prosthetic devices for the rehabilitation of patients with congenital or acquired defects has intensified in recent years. This paper gives an insight into the latest innovations and improvisations in the field of maxillofacial prosthodontics.
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