Background: Metopic suture is present between two halves of the frontal bone of the Skull of infants and children. By about 6-8 years, it disappears; the persistence of metopic suture is called Metopism. Aim: To study the incidence of Metopic suture in adult skulls of Nellore South coastal District of Andhra Pradesh. Materials and Methods: A study was conducted to observe the incidence of Metopic suture in adult skulls of Nellore south coastal district of Andhra Pradesh. For this purpose, 82 Skulls belonging to the Departments Anatomy and Forensic Medicine and Toxicology of Narayana Medical College, Nellore, are observed. Results: Two out of 82 skulls showed Metopism. Conclusion:The incidence of Metopism in the present study is 2.4% and is compared to similar studies.

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Background: Oral health is a mirror of general health. Certain risk factors are common between oral and systemic diseases. The absence of teeth also affects oral health by altering the quality of life. Hence, the nutritional changes occurring in elderly patients following prosthodontic rehabilitation are evaluated. Materials and Methods: A total of 100 patients who underwent prosthodontic treatment for missing teeth were included in the study. Twice measurement of nutritional parameters was done: Initially at the time of diagnosis and then 5 months following commencement of the prosthodontic treatment. Dental analysis, evaluation of the diet, anthropometric assessment, and analysis of serum biochemical values were done in all the patients, and tabulated records were maintained. Independent Student's t-test and Tukey's test were done to assess the level of significance. Results: A total of 100 patients were included in the study. The complete denture (CD) group showed the highest alteration in the mean values of the nutritional parameters followed by the removable partial denture group. A significant change was seen in the body mass index, protein, carbohydrate, and iron levels among the different patients who were grouped based on the mode of treatment modality. The CD group showed significantly higher mean change in carbohydrates value compared with mean change in patients receiving fixed treatment. Conclusion: Our results conclude that nutrition and diet form an integral part of prosthodontic treatment to maintain the health of elderly population.

Introduction: Dental pulp remains one of the important sources of mesenchymal stem cells for most preclinical and clinical studies. Aim and Objectives: To assess the safety after injecting human dental pulp-derived mesenchymal stem cells by intramucosal and intrabony routes in rabbits for clinical application. Materials and Methods: Animal studies were carried out among 30 New Zealand male white rabbits (3–5 months old), weighing 1.5–2 kgs, which were divided into three groups with 10 animals in each group. Group 1: control group, Group 2: intramucosal route, Group 3: intrabony route. Data were analyzed using Student's t -test, and any P ≤ 0.05 was statistically significant. Results: A total of 30 rabbits were selected for the study, among which significant statistical difference for Packed cell volume (PCV) ( P < 0.05), MCHC ( P < 0.05), platelet count ( P < 0.05), and ESR ( p < 0.001) has been reported in the hematological parameters. The results of the present study indicate that the transplantation of hDPSCs by intramucosal and intrabony routes into a rabbit is non-toxic without any detectable side effects or local or systemic rejection. The pre-clinical safety and toxicity of the hDPSCs in various human disease models need to be determined in future studies. Various pre-clinical studies to determine the safety and toxicity of hDPSCs in human disease models have to be done in the future. Conclusion: This study showed that the intramucosal route and intrabony route of administration of stem cells were found to be non-toxic at 10 million per mL concentration. A further evaluation must be done for more definitive results.