Cancer causes many deaths in the world. One of the most dangerous types of cancer is skin cancer caused by cancer cells that grow and spread uncontrollably in the skin layers. There are an estimated that 100,000 new cases of skin cancer will occur in the United States, which will cause around 6000 deaths by 2020. The survival rate of people with skin cancer can increase if successfully treated at an early stage. Examination of the lesion or dermoscopy images takes a long time and is prone to errors due to differences of opinion by doctors. A computer program for image processing was developed to improve accuracy and efficiency that helps doctors diagnose and evaluate. The most crucial stage in the diagnosis process is the segmentation of skin lesions. Wrong segmentation results will affect accuracy at the classification stage. This study developed a segmentation model for a skin cancer image that uses the MobileNet model as an encoder block and Linknet model for a decoder block by selecting the best hyper-parameter value from several training scenarios. MobileNet encoder and Linknet as a decoder are known to have the same ability, which is to overcome the problem of computational efficiency without compromising accuracy. Four hyper-parameters used are learning rate, the number of epochs, image size, and using pre-trained or not. Besides, there is a performance comparison scenario between the MobileNetV1 and MobileNetV2 encoder blocks. The model trained using the 2017 ISIC Challenge dataset consisting of 2000 training data, 150 validation data, and 600 test data. The Intersection over Union score obtained was 71.5% from models trained with a hyper-parameter learning rate of 0.001, 50 epochs, with an image size of 256 × 256 × 3, using a pre-trained model, and using a MobileNetV1 encoder block. The mask image that is the result of the segmentation of skin cancer images using the MobileNet encoder model and Linknet decoder is accurate enough to be used in the process at a later stage.
The synthesis of the hydrophobic silica layer was conducted using the sol–gel method by reacting silica precursor trimethylchlorosilane (TMCS) and tetraethylorthosilicate (TEOS) with variations in the precursor composition ratio (TMCS:TEOS) of 10:90, 25:75, 50:50, 75:25, and 90:10 and then calcined at various temperatures. The TMCS‐TEOS silica thin layer has a significant influence on the surface hydrophobicity of the glass. The higher the number of TMCS precursors, the greater the contact angle produced. The highest contact angle produced was 98° at a TMCS‐TEOS ratio of 75:25 and without calcination. The TMCS‐TEOS silica thin layer contact angle decreased with increasing calcination temperature. The hydrophobicity of the TMCS‐TEOS silica thin layer could withstand temperatures up to 300°C. Quantitative analysis of FTIR spectra's peak area shows that with the increasing TMCS, the ratio of silanol/siloxane decreases. Gas sorption analysis shows that the TMCS‐TEOS thin layers' pore sizes are in the mesoporous region, and the pore shapes are cylindrical at all TMCS:TEOS ratios and calcination temperatures.
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