The Thoracic Electrical Bioimpedance (TEB) helps to determine the stroke volume during cardiac arrest. While measuring cardiac signal it is contaminated with artifacts. The commonly encountered artifacts are Baseline wander (BW) and Muscle artifact (MA), these are physiological and nonstationary. As the nature of these artifacts is random, adaptive filtering is needed than conventional fixed coefficient filtering techniques. To address this, a new block based adaptive learning scheme is proposed to remove artifacts from TEB signals in clinical scenario. The proposed block least mean square (BLMS) algorithm is mathematically normalized with reference to data and error. This normalization leads, block normalized LMS (BNLMS) and block error normalized LMS (BENLMS) algorithms. Various adaptive artifact cancellers are developed in both time and frequency domains and applied on real TEB quantities contaminated with physiological signals. The ability of these techniques is measured by calculating signal to noise ratio improvement (SNRI), Excess Mean Square Error (EMSE), and Misadjustment (M ad ). Among the considered algorithms, the frequency domain version of BENLMS algorithm removes the physiological artifacts effectively then the other counter parts. Hence, this adaptive artifact canceller is suitable for real time applications like wearable, remove health care monitoring units.